AI Article Synopsis
- HRCT is favored over chest X-ray for initial assessment of sarcoidosis due to superior accuracy and fewer inconsistencies among radiologists.
- Chest X-rays have limitations in showing lung function and detecting critical lung issues compared to HRCT.
- HRCT also helps identify biopsy targets and new findings may correlate with significant prognostic outcomes, including mortality risks.
Article Abstract
In this review, we argue for the use of high-resolution computed tomography (HRCT) over chest X-ray in the initial evaluation of patients with sarcoidosis. Chest X-ray, which has long been used to classify disease severity and offer prognostication in sarcoidosis, has clear limitations compared with HRCT, including wider interobserver variability, a looser association with lung function, and poorer sensitivity to detect important lung manifestations of sarcoidosis. In addition, HRCT offers a diagnostic advantage, as it better depicts targets for biopsy, such as mediastinal/hilar lymphadenopathy and focal parenchymal disease. Newer data suggest that specific HRCT findings may be associated with important prognostic outcomes, such as increased mortality. As we elaborate in this update, we strongly recommend the use of HRCT in the initial evaluation of the patient with sarcoidosis.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958314 | PMC |
| http://dx.doi.org/10.12688/f1000research.11068.1 | DOI Listing |
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