AI Article Synopsis
- Intramural hematomas (IMHs) can lead to various outcomes, from regression to serious complications like aortic rupture, but there are no specific guidelines for management in China.
- A study tracked 123 IMH patients over an average of 20 months to assess clinical outcomes and identify predictors for aortic-related events.
- Results showed that a maximum aortic diameter (MAD) of 44.75 mm or greater and the presence of acute penetrating aortic ulcers were strong indicators of potential aorta-related complications, suggesting that careful monitoring and medication are essential for certain patient groups.
Article Abstract
Background: Intramural hematomas (IMHs) are reported to dynamically evolve into different clinical outcomes ranging from regression to aortic rupture, but no practice guidelines are available in China.
Objective: To determine the evolution of IMHs after long-term follow-up and to identify the predictive factors of IMH outcomes in the Chinese population.
Methods: A total of 123 IMH patients with clinical and imaging follow-up data were retrospectively studied. The primary endpoints were aortic disease-related death, aortic dissection, penetrating aortic ulcer (PAU), thickening of the aortic hematoma and aortic complications requiring surgical or endovascular treatment.
Results: All 123 IMH patients were monitored clinically. The follow-up duration ranged from 1.4 to 107 months (median, 20 months). Thirty-nine patients had type A IMH, and 84 had type B. The multivariate analysis showed that a baseline MAD ≥ 44.75 mm (2.9% vs 61.4%, P < 0.001) and acute PAUs (2.9% vs 34.1%, P = 0.008) were independent predictors of aorta-related events.
Conclusions: Medication and short-term imaging are recommended for Chinese IMH patients with a hematoma thickness < 10.45 mm and a baseline MAD < 44.75 mm. Rigorous medical observation should also be performed during the acute phase of IMH.
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| http://dx.doi.org/10.1016/j.ijcard.2018.06.077 | DOI Listing |
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