AI Article Synopsis
- Ingestion of house dust poses health risks to young children due to exposure to contaminants like bisphenol A (BPA), alkylphenols (APs), and alkylphenol ethoxylates (APEOs).
- A new method was developed to accurately measure these contaminants in house dust, using a combination of solvent extraction, solid-phase extraction, and advanced analysis techniques.
- The method showed high sensitivity and reliability, successfully detecting multiple target analytes with recoveries between 82-115%, making it useful for similar environmental studies involving sediments and soil.
Article Abstract
Ingestion of house dust has been demonstrated to be an important exposure pathway to several contaminants in young children. These compounds include bisphenol A (BPA), alkylphenols (APs), and alkylphenol ethoxylates (APEOs). Analysis of these compounds in house dust is challenging because of the complex composition of the sample matrix. The objective was to develop a simple and sensitive method to measure BPA, APs, and APEOs in indoor house dust. An integrated method that involved solvent extraction using sonication, sample cleanup by solid-phase extraction, derivatization by 2,2,2-trifluoro--methyl--(trimethylsilyl)acetamide, and analysis by GC coupled with tandem MS was developed for the simultaneous determination of BPA, APs, and APEOs in NIST Standard Reference Material (SRM) 2585 (Organic contaminants in house dust) and in settled house dust samples. Target analytes included BPA, 4--octylphenol (OP), OP monoethoxylate, OP diethoxylate, 4--nonylphenol (4NP), 4NP monoethoxylate (4NPEO), branched nonylphenol (NP), NP monoethoxylate, NP diethoxylate, NP triethoxylate, and NP tetraethoxylate. The method was sensitive, with method detection limits ranging from 0.05 to 5.1 μg/g, and average recoveries between 82 and 115%. All target analytes were detected in SRM 2585 and house dust except 4NP and 4NPEO. The method is simple and fast, with high sensitivity and good reproducibility. It is applicable to the analysis of target analytes in similar matrixes, such as sediments, soil, and biosolids. Values measured in SRM 2585 will be useful for future research in method development and method comparison.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5740/jaoacint.18-0071 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Occupational exposure and sarcoidosis: a case-control study in three countries.
Occup Med (Lond)
January 2025
MTW-Holding, Minsk 220070, Belarus.
Background: Preceding studies of environmental and occupational risk factors of sarcoidosis yielded inconsistent findings.
Aims: We aimed to ascertain the occupational risk factors for sarcoidosis in a case-control study.
Methods: A total of 237 sarcoidosis patients with a histologically confirmed diagnosis were matched with 474 controls for sex and age (median 49, interquartile range 37; 60 years) recruited from the university hospitals and outpatient centres in Belarus, Kazakhstan and the Russian Federation.
Efficacy of Subcutaneous, Sublingual and Oral Immunotherapy for Allergens: A Comparative Study.
Immunology
January 2025
Department of Allergology, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
The purpose of this study was to compare the efficacy and safety of subcutaneous, sublingual, oral specific immunotherapy in patients who suffer from allergic conditions to pollen from trees, grasses and weeds, house dust mites and Alternaria alternata spores. A literature search was performed separately for each type of allergen and each administration route of the drug. As a result, it was found that all administration routes were quite effective.
View Article and Find Full Text PDFComplicated pollution characteristics (particulate matter, heavy metals, microplastics, VOCs) of spent lithium-ion battery recycling at an industrial level.
Sci Total Environ
January 2025
School of Environmental Science and Engineering, Shanghai Jiao Tong University, 200240, China.
The recycling of spent lithium-ion batteries has become a common concern of the whole society, with a large number of studies on recycling management and recycling technology, but there is relatively little study on the pollution release during the recycling process. Pollution will restrict the healthy development of the recycling industry, which makes relevant research very significant. This paper monitored and analyzed the battery recycling pretreatment process in a formal factory, and studied the pollution characteristics of particulate matter, heavy metals, and microplastics under different treatment stages.
View Article and Find Full Text PDFMaternal Bisphenol A Exposure Induces Hippocampal-Dependent Learning and Memory Deficits Through the PI3K/Akt/mTOR Pathway in Male Offspring Rats.
J Biochem Mol Toxicol
January 2025
Medical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, China.
Bisphenol A (BPA), an environmental endocrine disrupting chemical, is one of the most widely used chemicals in the world and is widely distributed in the external environment, specifically in food, water, dust, and soil. BPA exposure is associated with abnormal cognitive behaviors. However, the underlying mechanism remains unclear.
View Article and Find Full Text PDFCMPK2 promotes NLRP3 inflammasome activation via mtDNA-STING pathway in house dust mite-induced allergic rhinitis.
Clin Transl Med
January 2025
Allergy Center, Department of Otolaryngology, Affiliated Eye and ENT Hospital, Fudan University, Shanghai, China.
Background: House dust mite (HDM) is the leading allergen for allergic rhinitis (AR). Although allergic sensitisation by inhaled allergens renders susceptible individuals prone to developing AR, the molecular mechanisms driving this process remain incompletely elucidated.
Objective: This study aimed to elucidate the molecular mechanisms underlying HDM-induced AR.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!