Three aryl-tetralin-type lignans, including 2 previously undescribed compounds, were isolated from the root of . The structures of the new compounds were elucidated by 1D- and 2D-NMR spectroscopic analyses and mass spectrometry. Experimental and calculated ECD were used to determine the absolute configurations. The isolated compounds were evaluated for cytotoxicity against two cell lines (MV4-11 and MDA-MB-231) and compound exhibited moderate growth inhibition against MDA-MB-231 cell line with IC value of 15.76 μM.
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| http://dx.doi.org/10.1080/10286020.2018.1487957 | DOI Listing |
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