Gastric duplication cyst with elevated CEA level: a case report.

J Surg Case Rep

Department of Abdominal Surgery, Epicura Hospital, 7301 Hornu, Belgium.

Published: May 2018

Gastrointestinal tract duplications are congenital malformations rarely seen in adulthood. Gastric duplications (GD) represent 2-9% of it. Malignant transformation of GD is a rare complication described in the literature. We present the case of a 43-year-old man, who presented an abdominal mass and an elevated CEA level. A total gastrectomy was performed and the histological examination described a gastric duplication cysts (GDC) without malignant transformation. It is not the first case of elevation of CEA in GDC without evidence of malignancy described in the literature. Some authors think that GDC are premalignant lesions that envolve with the time to carcinomas. It is recommend that once the GDC is diagnosed to remove surgically the entire cyst even if the patient is asymptomatic.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007364PMC
http://dx.doi.org/10.1093/jscr/rjy114DOI Listing

Publication Analysis

Top Keywords

gastric duplication
8
elevated cea
8
cea level
8
malignant transformation
8
described literature
8
duplication cyst
4
cyst elevated
4
level case
4
case report
4
report gastrointestinal
4

Similar Publications

Background: Gastric duplication (GD) is a rare congenital gastrointestinal malformation, and usually identified in childhood. This study aimed to investigate the clinical characteristics and treatment of GDs in children.

Methods: A retrospective review was conducted of medical records of 38 patients with the diagnosis of GD, treated in the Department of General Surgery, Children's Hospital of Zhejiang University School of Medicine, within the period from August 2013 to December 2023.

View Article and Find Full Text PDF

F. Zhang and H. Luo, "Diosmetin Inhibits the Growth and Invasion of Gastric Cancer by Interfering With M2 Phenotype Macrophage Polarization," Journal of Biochemical and Molecular Toxicology 37, no.

View Article and Find Full Text PDF

Gastric duplication cysts (GDCs) are rare congenital anomalies, often identified during infancy or childhood. Although typically benign, there have been sporadic reports of malignant transformations, including adenocarcinoma and rare mixed tumors. Herein, we describe a rare case of mixed pancreatobiliary ductal adenocarcinoma and squamous cell carcinoma occurring within a GDC in a 54-year-old Korean woman with a history of melena and hematemesis.

View Article and Find Full Text PDF

Objective: To critically analyse literature on the anticancer properties of andrographolide in studies on gastric cancer cells.

Method: This study systematically reviewed articles from 2013 to 2024 across five prominent databases; PubMed, Google Scholar, Web of Science, Scopus, and Science Direct, EMBASE, Cochrane library and DOAJ. The study eligibility criteria include original studies assessing using gastric cancer cell lines and articles utilizing extracted andrographolide from or standard andrographolide source treatment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!