Uveitis and internuclear ophthalmoplegia as ocular manifestations of sarcoidosis.

Saudi J Ophthalmol

Department of Surgery, Ophthalmology Unit, Augusto Murri Hospital, ASUR 4, Fermo, Italy.

Published: January 2018

Sarcoidosis is a multisystemic granulomatous chronic disease of unknown etiology with a wide range of clinical presentations. Diagnosis of sarcoidosis in patients with ocular manifestations can be challenging. We first describe a case of sarcoidosis presented with pulmonary involvement and both uveitis and internuclear ophthalmoplegia as ocular manifestations. A 55-year-old caucasian woman with non-productive cough and weakness presented with bilateral granulomatous anterior uveitis. Few days later, the patient presented again complaining of horizontal diplopia due to internuclear ophthalmoplegia. The diagnosis of sarcoidosis was made as a result of clinical examination and systemic investigations. Particularly, high-resolution computed tomography scanning of the chest was able to identify bilateral hilar lymphadenopathy not previously detected by chest X-ray. Biopsy confirmed diagnosis showing classic non-caseating granulomas.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010614PMC
http://dx.doi.org/10.1016/j.sjopt.2017.12.003DOI Listing

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