Sewage sludge (SS) and deinking sludge (DS) were used to comparatively study the hydrothermal dewatering of sludge with different components. For a better overview, an insight into the relationship between physicochemical properties and dewaterability of hydrothermal sludge was provided. Results found that not all kinds of sludge were suitably conditioned by hydrothermal treatment (HT) in term of the elevation of dewaterability. Higher hydrothermal temperature tended to enhance the dewaterability of SS rather than DS, which was supported by the variation of their physicochemical properties (including water distribution, bonding energy, extracellular polymeric substance (EPS), particles size, acid functional groups and zeta potential in this study). In addition, the changes in surface morphology suggested that the reverse effect of HT on sludge dewaterability was mainly due to their dewatering behavior. For SS, the destruction of EPS structure leaded to the release of bound water, thereby strengthening sludge dewatering. Conversely, "Bridging effect" generated by lignocellulose in DS was beneficial for sludge dewatering; however, the increasing hydrothermal temperature degraded part of lignocellulose and weakened "bridging effect", finally resulting in worse dewaterability of DS.
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http://dx.doi.org/10.1016/j.jes.2017.10.021 | DOI Listing |
Plant Foods Hum Nutr
January 2025
Post Graduate Program in Food Science and Technology, Federal University of Sergipe, Av. Marcelo Deda Chagas, s/n, Jardim Rosa Elze, São Cristóvão, 49100-000, SE, Brazil.
The plant specie, lemon balm (Melissa officinalis L.) is one of the most important species of the Lamiaceae family and its use as a plant extract has been highlighted by the population and the scientific community due to its rich chemical composition and the presence of bioactive compounds with potential antioxidant activity, associated with various health benefits. Research and development of innovative technologies are focused on the identification of these substances, their properties and applications.
View Article and Find Full Text PDFJ Mater Chem B
January 2025
Department of Optical and Biophysical Systems, Institute of Physics of the Czech Academy of Sciences, Prague, 18200, Czech Republic.
DNA nanostructures (DNs) have gained popularity in various biomedical applications due to their unique properties, including structural programmability, ease of synthesis and functionalization, and low cytotoxicity. Effective utilization of DNs in biomedical applications requires a fundamental understanding of their interactions with living cells and the mechanics of cellular uptake. Current knowledge primarily focuses on how the physicochemical properties of DNs, such as mass, shape, size, and surface functionalization, affect uptake efficacy.
View Article and Find Full Text PDFJ Chem Inf Model
January 2025
Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Skin corrosion assessment is an essential toxicity end point that addresses safety concerns for topical dosage forms and cosmetic products. Previously, skin corrosion assessments required animal testing; however, differences in skin architecture and ethical concerns regarding animal models have fostered the advancement of alternative methods such as and models. This study aimed to develop deep learning (DL) models based on recurrent neural networks (RNNs) for classifying skin corrosion of chemical compounds based on chemical language notation, molecular substructure, physicochemical properties, and a combination of these three properties called conjoint fingerprints.
View Article and Find Full Text PDFChembiochem
January 2025
Southeast University, School of Biological Science and Medical Engineering, 2 Sipailou, Xuanwu District, 210096, Nanjing, CHINA.
In recent years, antimicrobial peptides (AMPs) have emerged as a potent weapon against the growing threat of antibiotic resistance. Among AMPs, the ones containing tryptophan (W) and arginine (R) exhibit enhanced antimicrobial properties, benefiting from the unique physicochemical features of the two amino acids. Herein, we designed three hexapeptides, including WR, DWR (D-isomer), and RF, derived from the original sequence, RWWRWW-NH2 (RW).
View Article and Find Full Text PDFBiomater Sci
January 2025
Department of Bio and Brain Engineering, and KAIST Institute for Health Science and Technology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea.
Incorporation of polyethylene glycol (PEG) is widely used in lipid nanoparticle (LNP) formulation in order to achieve adequate stability due to its stealth properties. However, studies have detected the presence of anti-PEG neutralizing antibodies after PEGylated LNP treatment, which are associated with anaphylaxis, accelerated LNP clearance and premature release of cargo. Here, we report the development of LNPs incorporating ganglioside, a naturally occurring stealth lipid, as a PEG-free alternative.
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