[This corrects the article DOI: 10.1371/journal.pone.0130353.].
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199895 | PLOS |
J Neurol
January 2025
Department of Neurology, School of Medical Sciences, University of Campinas-UNICAMP, Universitaria "Zeferino Vaz", Rua Tessália Vieira de Camargo, 126. Cidade, Campinas, SP, 13083-887, Brazil.
Background: Skeletal and cardiac muscle damage have been increasingly recognized in female carriers of DMD pathogenic variants (DMDc). Little is known about cognitive impairment in these women or whether they have structural brain damage.
Objective: To characterize the cognitive profile in a Brazilian cohort of DMDc and determine whether they have structural brain abnormalities using multimodal MRI.
Aging Dis
January 2025
School of Public Health, University of Haifa, Haifa 3498838, Israel.
The role of endogenous cannabinoids (endocannabinoids; eCBs) in cognitive-related processes has been demonstrated in preclinical studies. However, observational studies are lacking. We examined the associations of multiple circulating eCBs and eCB-like molecules with cognitive function in a sample of dementia-free older adults.
View Article and Find Full Text PDFActa Neurobiol Exp (Wars)
January 2025
Laboratory of Animal Models, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.
The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) gene is a critical tumor suppressor that plays an essential role in the development and functionality of the central nervous system. Located on chromosome 10 in humans and chromosome 19 in mice, PTEN encodes a protein that regulates cellular processes such as division, proliferation, growth, and survival by antagonizing the PI3K‑Akt‑mTOR signaling pathway. In neurons, PTEN dephosphorylates phosphatidylinositol‑3,4,5‑trisphosphate (PIP3) to PIP2, thereby modulating key signaling cascades involved in neurogenesis, neuronal migration, and synaptic plasticity.
View Article and Find Full Text PDFJ Educ Health Promot
November 2024
Higher Institute of Nursing Professions and Techniques of Health of Fez, Fez, Morocco.
Background: Psychological flourishing is a component of positive mental health that characterizes the lives of nursing and health technology students, despite the stressful situations they experience during this training. The objective of this study is to evaluate psychological flourishing and to put the thumb on its importance in the training of nursing and health technique students.
Materials And Methods: A cross-sectional descriptive-analytical study was conducted at the two higher institutes of nursing and health technical professions in Fez and Rabat between 1 March and 30 March 2022, using a questionnaire containing socio-demographic characteristics, training characteristics, a perceived stress scale (PSS10) and a psychological flourishing scale.
Alzheimers Dement (Amst)
January 2025
Department of Neurology Massachusetts General Hospital, Harvard Medical School Boston Massachusetts USA.
Introduction: Timely detection and tracking of Alzheimer's disease (AD) -related cognitive decline has become a public health priority. We investigated whether the NIH Toolbox for Assessment of Neurological and Behavioral Function-Cognition Battery (NIHTB-CB) detects AD-related cognitive decline.
Methods: = 171 participants (age 76.
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