Background: Cleft lip and palate is a relatively common condition presenting a considerable technical challenge, especially the wide cleft (>8 mm), for the surgeons. Pre-surgical orthodontics, which reduces the cleft width and facilitates definitive repair, is expensive and not universally available, especially in the third world. Lip adhesion could be a cheaper alternative to pre-surgical orthodontics.
Methods: This six-year prospective observational study, from 2010 to 2016, was conducted at the paediatric surgical units of PNS Shifa Hospital, Karachi and Military Hospital Rawalpindi. All children with wide (8 mm or more gap in the alveolus) complete ULCP (unilateral cleft lip and palate) were included in the study. Lip adhesion with concomitant vomer flap palatal repair was followed by definitive lip repair once the desired moulding, i.e., alveolar gap <5 mm or adequate narrowing as per surgeon's subjective assessment during the 3 and 6 monthly follow up, had been achieved.
Results: A total of 53 children with the mean age 4.5±1.5 months were subjected to surgery, 32 (60.4 %) were males and 21 (39.6%) were females. The mean gap in the cleft alveolus was 11.1±1.7 mm, which was reduced to a mean of 3.2±1.3 mm, after a follow up of 4.3±1.1 months. The outcome of the lip repair, based on parental satisfaction, was excellent in 41 (77.3%), good in 10 (18.9%) and poor in 2 (3.8%) cases.
Conclusions: Lip adhesion is a safe and effective substitute for pre-surgical orthodontics in wide ULCP.
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Algorithms
December 2023
Fetal-Neonatal Neuroimaging and Developmental Science Center, Division of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Commun Med (Lond)
December 2024
Senior Department of Otolaryngology-Head and Neck Surgery, the Sixth Medical Center of PLA General Hospital, Beijing, 100048, China.
Background: Cochlear implants have helped over one million individuals restore functional hearing globally, but their clinical utility in suppressing tinnitus has not been firmly established.
Methods: In a decade-long study, we examined longitudinal effects of cochlear implants on tinnitus in 323 post-lingually deafened individuals including 211 with pre-existing tinnitus and 112 without tinnitus. The primary endpoints were tinnitus loudness and tinnitus handicap inventory.
J Man Manip Ther
November 2024
Unidad de Investigación en Fisioterapia, Faculty of Health Science, Universidad de Zaragoza, Zaragoza, Spain.
Introduction: Carpal Tunnel Syndrome (CTS) is a prevalent upper limb mononeuropathy that often leads to delayed surgical intervention, resulting in prolonged symptoms and reduced quality of life.
Aim: To describe the effect of a three-session treatment involving nerve mechanical interface mobilization and self-mobilization combined with education in hand function, symptoms, and quality of life of pre-surgical CTS patients at 3 and 6-months follow-ups; 3) A randomized clinical trial was performed in 42 preoperative CTS patients. Patients were randomized into an experimental group, receiving a three-session intervention of education, diacutaneous fibrolysis, and self-mobilization, or a control group receiving standard care.
Cureus
October 2024
Department of Anesthesiology, Uniformed Services University of the Health Sciences, Bethesda, USA.
Transl Pediatr
September 2024
Department of Neuroradiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Background And Objective: Epilepsy affects approximately 50 million people worldwide, with 30-40% of patients not responding to medication, necessitating alternative therapies such as surgical intervention. However, the accurate localization of epileptogenic lesions, particularly in pediatric magnetic resonance imaging (MRI)-negative drug-resistant epilepsy, remains a challenge. This paper reviews advanced neuroimaging techniques aimed at improving the detection of such lesions to enhance surgical outcomes.
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