Should they stay or should they leave? The age at which young transition between life stages, such as living in a nest versus leaving it, differs among species and the reasons why are unclear. We show that offspring of songbird species that leave the nest at a younger age have less developed wings that cause poorer flight performance and greater mortality after fledging. Experimentally delayed fledging verified that older age and better developed wings provide benefits of reduced juvenile mortality. Young are differentially constrained in the age that they can stay in the nest and enjoy these fitness benefits because of differences among species in opposing predation costs while in the nest. This tension between mortality in versus outside of the nest influences offspring traits and performance and creates an unrecognized conflict between parents and offspring that determines the optimal age to fledge.
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http://dx.doi.org/10.1126/sciadv.aar1988 | DOI Listing |
J Leukoc Biol
January 2025
Department of Surgery, University of California, San Diego Health, San Diego, CA, USA.
Pediatric intensive care patients are particularly susceptible to severe bacterial infections because of ineffective neutrophil responses. The reasons why neutrophils of newborns are less responsive than those of adults are not clear. Because adenosine triphosphate (ATP) and adenosine (ADO) tightly regulate neutrophils, we studied whether the ATP and ADO levels in the blood of newborn mice could impair the function of their neutrophils.
View Article and Find Full Text PDFGeroscience
January 2025
Inflammation and Ageing, University of Birmingham, Birmingham, UK.
Individuals who suffer a major burn injury are at higher risk of developing a range of age-associated diseases prematurely leading to an increase in mortality in adult and juvenile burn injury survivors. One possible explanation is that injury is accelerating the biological ageing process. To test this hypothesis, we analysed DNA methylation in peripheral blood mononuclear cells from adult burn-injured patients (> 5%TBSA) upon admission to hospital and 6 months later, to calculate an epigenetic clock value which can be used to determine biological age.
View Article and Find Full Text PDFMod Rheumatol
January 2025
Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
[Objective] To investigate differences in autoantibodies, clinical features, and long-term outcomes between juvenile- and adult-onset systemic sclerosis (SSc). [Methods] Autoantibodies and survival rates over a maximum of 20 years were retrospectively analyzed in 504 Japanese patients with SSc (juvenile-onset SSc, n=17; adult-onset SSc, n=487) using data from Kyoto University Registry. [Results] The autoantibodies observed were anti-topoisomerase-I (71% vs.
View Article and Find Full Text PDFSci Rep
January 2025
Centro de Investigação em Biodiversidade e Recursos Genéticos, CIBIO-InBIO, Universidade do Porto, Campus Agrário de Vairão, r/ Padre Armando Quintas, Vairão, 4485-661, Portugal.
Populations of large pelagic sharks are declining worldwide due to overfishing. Determining the overlap between shark populations and fishing activities is important to inform conservation measures. However, for many threatened sharks the whereabouts of particularly vulnerable life-history stages - such as pregnant females and juveniles - are poorly known.
View Article and Find Full Text PDFEcol Evol
January 2025
Minderoo Foundation Perth Western Australia Australia.
Coral reefs worldwide are threatened by increasing ocean temperatures because of the sensitivity of the coral-algal symbiosis to thermal stress. Reef-building corals form symbiotic relationships with dinoflagellates (family Symbiodiniaceae), including those species which acquire their initial symbiont complement predominately from their parents. Changes in the composition of symbiont communities, through the mechanisms of symbiont shuffling or switching, can modulate the host's thermal limits.
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