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Three-dimensional digital model of the facial nerve assisted in the excision of benign parotid tumors based on 3D-DESS-WE-MRI.
Sci Rep
December 2024
Department of Stomatology, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Henan University People's Hospital, #7 Wei Wu Road, Zhengzhou, 450003, Henan, China.
This study proposes a novel surgical technique for the excision of benign parotid tumors, utilizing a extracapsular dissection guided by a three dimensional digital model of the facial nerve(3DFN-ECD) and compares its clinical efficacy with the extracapsular dissection (ECD) method. This prospective study included 68 patients with benign parotid tumors. The control group (40 patients) received the ECD treatment, while the experimental group (28 patients), underwent the 3DFN-ECD approach proposed in this study.
View Article and Find Full Text PDFAssessing the knowledge, attitudes and practices of healthcare staff and students regarding disposal of unwantead medications: a systematic review.
BMJ Open
December 2024
Department of Primary Care and Public Health, School of Public Health, Imperial College London Faculty of Medicine, London, UK
Objectives: We sought to review studies that examine healthcare professionals' and students' knowledge, attitudes and practices (KAP) regarding medication disposal. We also explore recommendations and barriers related to appropriate medication disposal.
Design: A systematic review was conducted that adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses.
Radioimmunotherapy combating biofilm-associated infection .
Front Med (Lausanne)
November 2024
Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands.
Background: Addressing prosthetic joint infections poses a significant challenge within orthopedic surgery, marked by elevated morbidity and mortality rates. The presence of biofilms and infections attributed to () further complicates the scenario.
Objective: To investigate the potential of radioimmunotherapy as an innovative intervention to tackle biofilm-associated infections.
The prevalence and impact of microaggressions within orthopaedics in the United States of America: A systematic review.
Surgeon
December 2024
Wythenshawe Hospital, Southmoor Rd, Wythenshawe, Manchester, M23 9LT, UK. Electronic address:
Background: Microaggressions are being increasingly documented within the medical community. With their rising prevalence, there is concern that microaggressions can lead to suboptimal working environments, victim burnout, and compromised patient safety. Orthopaedics, known for macroaggressions like bullying and sexual discrimination, remains the least diverse specialty, potentially predisposing its staff to microaggressions.
View Article and Find Full Text PDFNatural lung-tropic T9 cells: a sharp weapon for established lung metastases.
J Immunother Cancer
December 2024
Department of Orthopedics, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China
Article Synopsis
- Lung metastasis is a major cause of cancer death, with few effective treatments; T helper 9 (T9) cells show potential in treating tough cases like lung metastases, but more research on their biology is needed.* ! -
- The study involved transferring T1, T9, and T17 cells into different cancer models to compare their effectiveness, using techniques like flow cytometry and RNA sequencing to investigate the reasons behind T9 cells' superior ability to reach the lungs.* ! -
- Results revealed that T9 cells have a stronger ability to target lung metastases due to the CXCR4-CXCL12 pathway, and disabling CXCR4 reduces T9 cells' presence in the lungs, highlighting their
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