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| http://dx.doi.org/10.1113/JP276498 | DOI Listing |
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Rspo3-mediated metabolic liver zonation regulates systemic glucose metabolism and body mass in mice.
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January 2025
Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
The unique architecture of the liver consists of hepatic lobules, dividing the hepatic features of metabolism into 2 distinct zones, namely the pericentral and periportal zones, the spatial characteristics of which are broadly defined as metabolic zonation. R-spondin3 (Rspo3), a bioactive protein promoting the Wnt signaling pathway, regulates metabolic features especially around hepatic central veins. However, the functional impact of hepatic metabolic zonation, regulated by the Rspo3/Wnt signaling pathway, on whole-body metabolism homeostasis remains poorly understood.
View Article and Find Full Text PDFInternal Tremor in Long COVID May Be a Symptom of Dysautonomia and Small Fiber Neuropathy.
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December 2024
Center for Complex Neurology, University of Arizona College of Medicine, Phoenix, AZ 85004, USA.
Internal tremor (IT) is often reported by patients with post-acute sequelae of SARS-CoV-2, also known as Long COVID, as a distressing and disabling symptom. Similarly, physicians are typically perplexed by the nature and etiology of IT and find it extremely challenging to manage. We describe a patient with Long COVID who experienced IT as part of post-COVID postural orthostatic tachycardia syndrome (POTS) and small fiber neuropathy (SFN) and review the limited literature available on this topic.
View Article and Find Full Text PDFSubgroup Characteristics of Middle-Aged and Older Women with Chronic Low Back Pain by Multiple Factors: A Hierarchical Cluster Analysis.
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Department of Rehabilitation, Komatsu Sophia Hospital, 478 Okimachi, Komatsu 923-0861, Japan.
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View Article and Find Full Text PDFSex Influence on Trigeminal Nerve Stimulation and Breath-Hold Diving Performance: Examination of the Autonomic Regulation of Cardiovascular Responses to Facial Cooling and Apnoea Across Sex and Varied Factors.
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Department of Neurophysiology, Neuropsychology and Neuroinformatics, Medical University of Gdansk, 80-210 Gdansk, Poland.
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View Article and Find Full Text PDFInfluence of sex on sympathetic vasomotor outflow responses to passive leg raising in young individuals.
J Physiol Sci
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Department of Biomedical Engineering, Toyo University, Kawagoe, Japan.
The purpose of this study was to clarify sex differences in the inhibition of sympathetic vasomotor outflow which is caused by the loading of cardiopulmonary baroreceptors. Ten young males and ten age-matched females participated. The participants underwent a passive leg raising (PLR) test wherein they were positioned supine (baseline, 0º), and their lower limbs were lifted passively at 10º, 20º, 30º, and 40º.
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