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Tattooing: immediate and long-term adverse reactions and complications.
Arh Hig Rada Toksikol
December 2024
1University of Zagreb Faculty of Pharmacy and Biochemistry, Department of Medical Biochemistry and Haematology, Zagreb, Croatia.
Tattooing has become a popular global trend in industrialised countries, with the highest prevalence rates of up to 30-40 % in the adult population younger than 40 years. Common tattoo inks may contain heavy metals, polycyclic aromatic hydrocarbons, and primary aromatic amines, toxic if exceeding permissible limits. It is estimated that about 14.
View Article and Find Full Text PDFRole of Multimodality Imaging in Cardiac Sarcoidosis: A Retrospective Single-Center Experience.
J Clin Med
December 2024
Department of Cardiology, Icahn School of Medicine, Mount Sinai Morningside, New York, NY 10025, USA.
Cardiac sarcoidosis (CS) is a rare entity characterized by granulomatous infiltration of the myocardium, which can lead to myocardial fibrosis, conduction abnormalities, and the development of heart failure, thereby elevating the risk of sudden cardiac death (SCD). While endomyocardial biopsy (EMBx) is regarded as the gold standard for diagnosis, its low sensitivity and inherent procedural risks may limit its practical application. This study retrospectively explored the role of advanced imaging modalities, specifically cardiovascular magnetic resonance imaging (CMR) and fluorodeoxyglucose positron emission tomography (FDG-PET), in the diagnosis and management of CS within a single center.
View Article and Find Full Text PDFFrequency and consequences of immune checkpoint inhibitor-associated inflammatory changes in different organs: an autopsy study over 13-years.
Mod Pathol
December 2024
Department of Pathology and Molecular Pathology, University Hospital of Zurich, Switzerland; University of Zurich, Switzerland.
While immune checkpoint inhibitors (ICIs) have revolutionized modern oncology, they are also associated with immune-related adverse events (irAEs). Previous histopathological descriptions of organ-related inflammatory changes do not consider systemic effects of ICIs, because of an absence of comprehensive autopsy studies. We performed a retrospective study on 42 whole-body autopsies of patients treated with ICIs from January 2011 to March 2024 to determine frequency, organ distribution and morphology of ICIs-associated inflammatory changes as well as their clinical relevance.
View Article and Find Full Text PDFSuccessful surgical management of uveitic glaucoma in a sarcoidosis patient with cutaneous manifestations.
BMJ Case Rep
December 2024
Ophthalmology, Western Eye Hospital, Imperial College Healthcare NHS Trust, London, UK.
Sarcoidosis is a systemic granulomatous disease with variable ocular involvement. The most common ocular manifestation is uveitis, which can have potentially sight threatening complications such as glaucoma. We present the case of a man in his 30s with sarcoidosis and recurrent anterior uveitis, necessitating surgical intervention to control intraocular pressure and prevent further glaucomatous optic neuropathy progression.
View Article and Find Full Text PDFPrevalence of bovine paratuberculosis in Chinese cattle populations: a meta-analysis.
Front Cell Infect Microbiol
December 2024
Anhui Province Key Laboratory of Animal Nutritional Regulation and Health, Anhui Science and Technology University, Fengyang, China.
Background: Bovine paratuberculosis is a chronic infectious disease of ruminants primarily caused by (MAP). It is essentially a chronic granulomatous enteritis characterized by intractable diarrhea, progressive lethargy, and thickening of the intestinal mucosa with the formation of crumpled pouches. Bovine paratuberculosis not only adversely affects milk production and the quality of dairy products but also poses a significant threat to the economic development of dairy farming and human food security.
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