Objectives: To evaluate early quality of composite restorations with a universal adhesive in different application modes clinically and with optical coherence tomography (OCT).
Methods: 22 patients with four non-carious cervical lesions each received composite restorations (Filtek Supreme XTE, 3 M). The universal adhesive Scotchbond Universal(SBU, 3 M) was applied with three etching protocols: self-etch (SE), selective-enamel-etch (SEE) and etch-and-rinse (ER). The etch-and-rinse adhesive OptiBond FL (OFL, Kerr) served as a control. Restorations were imaged by OCT (Thorlabs) directly after application (t). After 14 days (t) and 6 month (t) OCT imaging (interfacial adhesive defects) was repeated combined with clinical assessment (FDI criteria). Groups were compared by Friedman-/Wilcoxon- and McNemar-Test.
Results: No differences were seen clinically between groups (p ≥ 0.500). OCT assessment revealed more adhesive defects at the enamel interface with SBU/SE at tt compared to all groups (p ≤ 0.016). OFL showed more defects than SBU/ER (t: p = 0.01; t: p = 0.083). At dentin/cementum interface OFL exhibited more adhesive defects than SBU with all conditioning modes (t, t, p ≤ 0.003) and at t to SBU/SE and SBU/ER (p < 0.001). Since t defects with SBU were detected more frequently in the SE and SEE modes compared to ER (p ≤ 0.037). In contrast to SBU defects increased with OFL up to t (p ≤ 0.007).
Conclusions: In contrast to clinical evaluation, OCT revealed subtle adhesive defects directly after application that might interfere with clinical success. It was demonstrated that ER does not decrease initial adhesion of SBU to dentin.
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http://dx.doi.org/10.1016/j.jdent.2018.06.007 | DOI Listing |
Vet Surg
January 2025
University Equine Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Objectives: To report the management and outcomes of five horses with ear skin defects treated with the use of full-thickness mesh grafts and full-thickness Meek micrografts.
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Study Design: Short case series.
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Department of Ophthalmology, Faculty of Medicine Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Anterior segment dysgenesis exerts its influence on a diverse array of ocular structures, encompassing the cornea, iris, ciliary body, anterior chamber and lens. We present a 20-month-old boy with bilateral corneal opacity. The visual acuity (VA) was 6/480 in both eyes.
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February 2025
State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China.
Inspired by the initial mineralization process with bone matrix vesicles (MVs), this study innovatively developed a delivery system to mediate mineralization during bone regeneration. The system comprises nanofibrous chitosan microspheres (NCM) and poly (allylamine hydrochloride)-stabilized amorphous calcium phosphate (PAH-ACP), which is thereafter referred to as NCMP. NCM is synthesized through the thermal induction of chitosan molecular chains, serving as the carrier, while PAH-ACP functions as the mineralization precursor.
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January 2025
Department of Orthopedics, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, 2800 Gongwei Road, Pudong, Shanghai 201300, China.
The application of light-responsive nanomaterials (LRNs) in bone tissue engineering shows broad prospects, especially in promoting bone healing and regeneration. With a deeper understanding of the mechanisms of bone defects and healing disorders, LRNs are receiving increasing attention due to their non-invasive, controllable, and efficient properties. These materials can regulate cellular biological reactions and promote bone cell adhesion, proliferation, and differentiation by absorbing specific wavelengths of light and converting them into physical and chemical signals.
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Division of Conservative Dentistry and Periodontology, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Over the past few years, biomaterial-based periodontal tissue engineering has gained popularity. An ideal biomaterial for treating periodontal defects is expected to stimulate periodontal-derived cells, allowing them to contribute most efficiently to tissue reconstruction. The present study focuses on evaluating the in vitro behavior of human periodontal ligament-derived stromal cells (hPDL-MSCs) when cultured on gelatin/Polycaprolactone prototype (GPP) and volume-stable collagen matrix (VSCM).
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