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| http://dx.doi.org/10.1007/s12079-018-0472-4 | DOI Listing |
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Molecular biomarkers of glial activation and injury in epilepsy.
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Faculty of Engineering and Science, University of Greenwich London, Chatham Maritime, ME4 4TB, UK; Faculty of Medicine, Tbilisi State University, Tbilisi 0179, Georgia. Electronic address:
Increasing evidence from fluid biopsies suggests activation and injury of glial cells in epilepsy. The prevalence of clinical and subclinical seizures in neurodegenerative conditions such as Alzheimer's disease, frontotemporal dementia, and others merits review and comparison of the effects of seizures on glial markers in epilepsy and neurodegenerative diseases with concomitant seizures. Herein, we revisit preclinical and clinical reports of alterations in glial proteins in cerebrospinal fluid and blood associated with various types of epilepsy.
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Faculty of Veterinary Medicine, Department of Clinical Sciences, Utrecht University, Utrecht, The Netherlands.
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Sevim Akbal is an assistant professor at Trakya University, Edirne/Kesan, Turkey, and Meltem Yildirim is a professor of nursing at the University of Vic-Central University of Catalonia, Vic, Catalonia, Spain. This study was presented at the 9th National-1st International Orthopedics and Traumatology Nursing Congress; October 23-26, 2019; Antalya, Turkey. Contact author: Sevim Akbal, The authors have disclosed no potential conflicts of interest, financial or otherwise.
Background: Total knee arthroplasty (TKA) is a surgical procedure to improve the quality of life of patients with osteoarthritis. However, postoperative recovery can be difficult due to sleep disturbance, such as poor sleep quality, and postsurgical pain.
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