AI Article Synopsis
- Dogs with canine leishmaniosis (CanL) present varying clinical symptoms, and this paper explores the role of acute phase proteins (APPs) in understanding and managing the disease.
- The study categorizes infected dogs into three groups based on clinical signs and APP levels: Group 1 has no symptoms and normal APPs, Group 2 shows APP changes without symptoms, and Group 3 has symptoms with altered APPs.
- The findings suggest that measuring APP concentrations can effectively aid in diagnosing and managing CanL in dogs.
Article Abstract
Background: Dogs with canine leishmaniosis (CanL) due to Leishmania infantum can show a wide spectrum of clinical and clinicopathological findings at the time of diagnosis. The aim of this paper is to describe the possible application of acute phase proteins (APPs) for the characterization and management of this disease, based on previously published information on the utility of APPs in CanL and the experience of the authors in using APPs as analytes in the profiling of canine diseases.
Main Body: Dogs diagnosed with L. infantum infection by serology, polymerase chain reaction, cytological or histopathological identification, can be divided into three groups based on their clinical condition at physical examination and their APPs concentrations: Group 1: dogs with no clinical signs on physical examination and APPs in reference range; Group 2: dogs with changes in APPs but no clinical signs on physical examination; Group 3: dogs with clinical signs and changes in APPs. This report describes the main characteristics of each group as well as its association with the clinical classification schemes of CanL.
Conclusion: APPs concentration can be a useful clinical tool to characterize and manage CanL.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011270 | PMC |
| http://dx.doi.org/10.1186/s12917-018-1524-y | DOI Listing |
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