Systematically electron microscopical control of BLV producing cells and stimulated lymphocytes of leukotic cattle in the last years revealed maturation processes of BLV in a different form from comparable type C viruses. Electron microscopic representation of bridge-like junctions between core and envelope within examined retroviruses were discussed and compared with new model concepts.
Download full-text PDF |
Source |
---|
Mater Horiz
January 2025
Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89081, Ulm, Germany.
This work involves the preparation of dual surrogate-imprinted polymers (D-MIPs) for the capture of SARS-CoV-2. To achieve this goal, an innovative and novel dual imprinting approach using carboxylated-polystyrene (PS-COOH) nanoparticles with a diameter of 100 nm and a SARS-CoV-2 Spike-derived peptide was carried out at the surface of amine-functionalized silica (PS-NH) microspheres with a diameter of 500 nm. Firstly, PS-COOH nanoparticles with the same size and spherical shape as the SARS-CoV-2 virus were employed to form hemispherical indentations (HI) at the surface of the PS-NH microspheres (obtaining dummy particle-imprinted polymers, HI-MIPs).
View Article and Find Full Text PDFJ Sep Sci
January 2025
Guangzhou Institute of Chemistry, Chinese Academy of Sciences, Guangzhou, China.
Per- and polyfluoroalkyl substances (PFAS) are a widely used class of synthetic chemicals that pose a significant global environmental and health threat due to their persistent and bioaccumulation toxicity caused by strong C-F bonds in their structures. PFAS usually exist in trace concentrations in environmental water bodies, which poses great challenges for environmental analysis. In this study, environmentally friendly cellulose was modified with polyaniline through in situ oxidative polymerization, and used as the filter paper for solid-phase extracting 23 PFAS in water.
View Article and Find Full Text PDFiScience
January 2025
Blue Brain Project, École Polytechnique Fédérale de Lausanne (EPFL), Campus Biotech, 1202 6 Geneva, Switzerland.
We hypothesized that the heterogeneous architecture of biological neural networks provides a substrate to regulate the well-known tradeoff between robustness and efficiency, thereby allowing different subpopulations of the same network to optimize for different objectives. To distinguish between subpopulations, we developed a metric based on the mathematical theory of simplicial complexes that captures the complexity of their connectivity by contrasting its higher-order structure to a random control and confirmed its relevance in several openly available connectomes. Using a biologically detailed cortical model and an electron microscopic dataset, we showed that subpopulations with low simplicial complexity exhibit efficient activity.
View Article and Find Full Text PDFRSC Adv
January 2025
National Centre of Excellence in Physical Chemistry, University of Peshawar Peshawar Pakistan.
In this study, a binary composite adsorbent based on activated carbon and phosphoric acid geopolymer foam (ACP) was prepared by combining phosphoric acid geopolymer (PAGP) with activated carbon (AC) and applied for the removal of methylene blue (MB). Activated carbon was thoroughly mixed with a mixture of fly ash and metakaolin in varying ratios, followed by phosphoric acid activation and thermal curing. The ACP adsorbent was characterized using scanning electron microscope (SEM), Fourier transform infrared (FTIR) spectrophotometer, X-ray diffractometer (XRD), surface area analyser (SAP), and thermogravimetric analyser (TGA).
View Article and Find Full Text PDFNat Commun
January 2025
Center of Cryo-Electron Microscopy, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
The multi-enzyme pyruvate dehydrogenase complex (PDHc) links glycolysis to the citric acid cycle and plays vital roles in metabolism, energy production, and cellular signaling. Although all components have been individually characterized, the intact PDHc structure remains unclear, hampering our understanding of its composition and dynamical catalytic mechanisms. Here, we report the in-situ architecture of intact mammalian PDHc by cryo-electron tomography.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!