Biomass fast pyrolysis oils contain molecules having a large variety of chemical functions and a wide range of molecular weights (from several tens to several thousand grams per mole). The good knowledge of their complex composition is essential for optimizing the conversion of bio-oils to biofuels, thereby requiring powerful separation techniques. In this work, we investigate the interest of centrifugal partition chromatography (CPC) as a first dimension for the analysis of a bio-oil. A CPC method is proposed to separate oxygen containing compounds according to their partition coefficients in the solvent system. This approach is a powerful and easy-to-use technique that enables fractionation of a bio-oil at a semi-preparative scale, without any sample loss related to adsorption on the stationary phase. Collected fractions are then injected in liquid chromatography as a second dimension of separation. Contour plot representations of the CPC × LC separation are established to discuss the potential of this approach. These representations can be used as a veritable fingerprint in the comparison of different samples or samples at different steps of a conversion process but also as a powerful tool to identify new compounds and describe the entire composition of the bio-oil.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.aca.2018.04.040 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Can Magnoflorine Improve Memory? Immunohistochemical Studies on Parvalbumin Immunoreactive Neurons and Fibers of Mice Hippocampus.
Nutrients
December 2024
Department of Pharmacognosy with Medicinal Plant Garden, Medical University in Lublin, 1 Chodzki St., 20-093 Lublin, Poland.
: We assessed the influence of long-term injection of magnoflorine (MAG) on memory acquisition in mice for the first time. : This isoquinoline alkaloid that belongs to the aporphines was isolated from the roots of by centrifugal partition chromatography (CPC) using a biphasic solvent system composed of chloroform: methanol: water in the ratio 4:3:3 (//) with 20 mM of hydrochloric acid and triethylamine, within 64 min. : Our results indicated that long-term injection of MAG 20 mg/kg dose improve the long-term memory acquisition in mice that were evaluated in the passive avoidance (PA) test with no toxicity records.
View Article and Find Full Text PDFArtificial molecular communication network based on DNA nanostructures recognition.
Nat Commun
January 2025
Key Laboratory for Organic Electronics and Information Displays (KLOEID), Nanjing University of Posts and Telecommunications, Nanjing, China.
Artificial simulated communication networks inspired by molecular communication in organisms use biological and chemical molecules as information carriers to realize information transmission. However, the design of programmable, multiplexed and general simulation models remains challenging. Here, we develop a DNA nanostructure recognition-based artificial molecular communication network (DR-AMCN), in which rectangular DNA origami nanostructures serve as nodes and their recognition as edges.
View Article and Find Full Text PDFBioactivity-guided identification of cytotoxic compounds from Tournefortia hirsutissima L. by Fast Centrifugal Partition Chromatography.
J Ethnopharmacol
December 2024
Tecnologico de Monterrey, Escuela de Ingeniería y Ciencias, Ave. Eugenio Garza Sada 2501, Monterrey, 64849, N.L., Mexico; Tecnológico de Monterrey, Institute for Obesity Research, Av. Eugenio Garza Sada 2501 Sur., Monterrey, 64849, N.L., Mexico. Electronic address:
Ethnopharmacological Relevance: Cancer is one of the leading causes of death in the world, where cervical cancer is the fourth leading cause of death in women. Existing treatments, although effective, have various adverse effects and often require a combination of two or more therapies. Previous studies have shown that different plant species of the genus Tournefortia sp.
View Article and Find Full Text PDFCan NMR-HetCA be a Reliable Prediction Tool for the Direct Identification of Bioactive Substances in Complex Mixtures?
Anal Chem
December 2024
Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece.
Conventional isolation methods in natural products chemistry are time-consuming and costly and often result in the isolation of moderately active compounds or the detection of already known natural products (NPs). A fast and cost-effective way to identify bioactive metabolites in plant extracts prior to isolation has been developed based on the nuclear magnetic resonance (NMR)-heterocovariance approach (NMR-HetCA). In order to evaluate in depth the application of this chemometrics-based drug discovery methodology, simple mixtures of 10 standard NPs simulating a fast centrifugal partition chromatography (FCPC) fractionation (artificial fractions, ArtFrcts), as well as a more complex mixture of 59 natural standard substances simulating a crude plant extract (artificial extract, ArtExtr), were prepared.
View Article and Find Full Text PDFA Metabolomics Strategy Combining Countercurrent Separation and qNMR for the Comprehensive Chemical Evaluation of Polygoni Multiflori Radix Processing.
Phytochem Anal
November 2024
College of Pharmacy, Yeungnam University, Gyeongsan-si, Gyeongsangbuk-do, Republic of Korea.
Introduction: Polygoni Multiflori Radix (PMR) is commonly used in traditional medicine as both raw and processed forms. Raw PMR was prepared into processed PMR via processing procedure; however, there is a lack of standardized protocols ensuring the completeness of processing.
Objective: This aims to develop a strategy based on a metabolomics approach for the comprehensive chemical profiling and comparison of raw and processed PMR and establish a basis for PMR processing standardization.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!