Disseminated infection to immune activation.

Proc (Bayl Univ Med Cent)

Department of Internal Medicine, State University of New York Upstate Medical University, Syracuse, New York.

Published: July 2018

A 61-year-old woman with rheumatoid arthritis on chronic immunosuppression presented with fever. Laboratory studies demonstrated multiorgan failure with pancytopenia, elevation in liver function studies, and an elevated ferritin level, with a diagnosis of hemophagocytic lymphohistiocytosis confirmed on bone marrow biopsy. After initial treatment with chemotherapy, fungal blood cultures grew , prompting initiation of antifungal therapy, which resulted in successful treatment of -associated hemophagocytic lymphohistiocytosis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997038PMC
http://dx.doi.org/10.1080/08998280.2018.1465321DOI Listing

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