(Hetero)aryl substituted saturated cyclic amines are ubiquitous scaffolds in biologically active molecules. Metal-catalyzed cross-couplings between halogeno -heterocycles and organometallic species are efficient and modular reactions to access these attractive scaffolds. An overview of our work concerning the cobalt-catalyzed arylation of iodo-substituted cyclic amines is presented.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099817 | PMC |
| http://dx.doi.org/10.3390/molecules23061449 | DOI Listing |
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