After the publication of this work [1] an error was noticed in Fig. 3a and Fig. 5a.
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http://dx.doi.org/10.1186/s13058-018-0986-y | DOI Listing |
Breast Cancer Res
June 2018
Department of Medical Sciences, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111, USA.
After the publication of this work [1] an error was noticed in Fig. 3a and Fig. 5a.
View Article and Find Full Text PDFCurr Top Med Chem
May 2012
Skin Oncology Service, University Hospital Birmingham, Mindelsohn Way, Birmingham, B15 2WB, UK.
In-transit metastases occur in approximately 3% of melanoma patients, can be very symptomatic and survival in this group may be prolonged. Regional chemotherapy with melphalan delivered by isolated limb perfusion (ILP) or isolated limb infusion (ILI) are effective treatment options which are generally well tolerated. ILI is a less invasive and simpler alternative to ILP.
View Article and Find Full Text PDFToxicol Sci
February 2009
Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli county 350, Taiwan, [corrected] Republic of China.
Epidemiological evidence indicated that there was a synergistic interaction between arsenic and cigarette smoke on enhancement of lung cancer risk. Benzo[a]pyrene (B[a]P), a component in cigarette smoke, is one of the most carcinogenic compounds known. Animal studies have demonstrated that there were increased benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE) adduct formation and lung tumorigenesis in animals when they were coexposed to B[a]P and arsenic.
View Article and Find Full Text PDFCell Biol Int
November 2005
Data Management Service, Istituto Superiore di Sanità, 00161 Rome, Italy.
K562 cells exposed for 3 h to taxol or taxol plus tyrphostin AG957 exhibited a significant variation in the concentration of the water-soluble metabolites glutathione, myo-inositol and phosphorylcholine, as evaluated by (1)H NMR up to 72 h incubation in drug-free medium. Cells treated with both drugs showed an increase of glutathione and glutathione reductase at 24 h and a sharp decrease of myo-inositol between 8 and 24 h. Phosphorylcholine increased at 8 h both in taxol and taxol plus AG957-treated cells, which was then abruptly inverted to a significantly lower concentration at 24 h, subsequently increasing again to values higher than those found in taxol-treated and control cells.
View Article and Find Full Text PDFJ Hepatol
October 2003
Section of Internal Medicine, Department of Internal Medicine and Public Medicine, University of Bari, Piazza G. Cesare, 11-70124 Bari, Italy.
Background/aims: Mitochondrial glutathione has been postulated to affect mitochondrial function and liver regeneration.
Methods: Mitochondrial respiration, total and oxidized glutathione, and liver regeneration were assessed after partial hepatectomy in glutathione-depleted and in hypothyroid rats with/without supplementation of glutathione ester.
Results: Mitochondrial, cytosolic and circulating glutathione levels were lower in glutathione-depleted rats.
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