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Background: In intensity modulated radiation therapy (IMRT) quality assurance (QA), evaluation of QA result using a pass/non-pass strategy under an acceptance criterion often suffers from lack of information on how good the plan is in absolute manner. In this study, we suggested adding an index system, previously developed for dose painting technique, to current IMRT QA process for better understanding of QA result.
Methods: The index system consists of three indices, index of achievement (IOA), index of hotness (IOH) and index of coldness (IOC). As indicated by its name, IOA does measure the level of agreement. IOH and IOC, on the other hand, measure the magnitude of overdose and underdose, respectively. A systematic analysis was performed with three 1-dimensional hypothetical dose distributions to investigate the characteristics of the index system. The feasibility of the system was also assessed with clinical volumetric modulated arc therapy (VMAT) QA cases from 8 head & neck and 5 prostate patients. In both simulation studies, certain amount of errors was intentionally induced to each dose distribution. Furthermore, we applied the proposed system to compare calculated with actual measured data for a total of 60 patients (30 head & neck and 30 prostate cases). QA analysis was made using both the index system and gamma method, and results were compared.
Results: While the gamma evaluation showed limited sensitivity in evaluating QA result depending on the level of tolerance criteria used, the proposed indices tended to better distinguish plans in terms of the amount of errors. Hotness and coldness of prescribed dose in the plan could be evaluated quantitatively by the indices.
Conclusions: The proposed index system provides information with which IMRT QA result would be better evaluated, especially when gamma pass rates are identical or similar among multiple plans. In addition, the independency of the index system on acceptance criteria would help making clear communications among readers of published articles and researchers in multi-institutional studies.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003087 | PMC |
http://dx.doi.org/10.1186/s13014-018-1055-5 | DOI Listing |
Gastrointest Endosc
November 2024
Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA; The James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Electronic address:
Background And Aims: Interobserver agreement (IOA) among pancreaticobiliary (PB) pathologists in evaluating high-grade dysplasia and/or invasive carcinoma (HGD-IC) of IPMNs remains understudied. EUS-guided needle-based confocal endomicroscopy (nCLE) can evaluate papillary architecture in branch-duct (BD)-IPMNs. We assessed IOA among PB pathologists in classifying dysplasia in resected IPMNs and compared the performance of the Kyoto guidelines' high-risk stigmata (HRS) and pre-surgical EUS-nCLE against reclassified pathology.
View Article and Find Full Text PDFSci Rep
November 2024
Key Laboratory of Groundwater Resources and Environment, Ministry of Education, Jilin University, Changchun, 130021, China.
Amidst growing concerns over climate-induced extreme weather events, precise flood forecasting becomes imperative, especially in regions like the Chaersen Basin where data scarcity compounds the challenge. Traditional hydrologic models, while reliable, often fall short in areas with insufficient observational data. This study introduces a hybrid modeling approach that combines the deep learning capabilities of the Informer model with the robust hydrological simulation by the WRF-Hydro model to enhance runoff predictions in such data-sparse regions.
View Article and Find Full Text PDFSci Rep
August 2024
Faculty of Engineering, Hokkaido University, Kita 8, Nishi 5, Kita-Ku, Sapporo, 0608628, Japan.
The ground vibration caused by rock blasting is an extremely hazardous outcome of the blasting operation. Blasting activity has detrimental effects on both the ecology and the human population living in proximity to the area. Evaluating the magnitude of blasting vibrations requires careful evaluation of the peak particle velocity (PPV) as a fundamental and essential parameter for quantifying vibration velocity.
View Article and Find Full Text PDFComput Biol Med
September 2024
Key Laboratory of Speech Acoustics and Content Understanding, Institute of Acoustics, Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, China. Electronic address:
Respiratory diseases are one of the major health problems worldwide. Early diagnosis of the disease types is of vital importance. As one of the main symptoms of many respiratory diseases, cough may contain information about different pathological changes in the respiratory system.
View Article and Find Full Text PDFClin Ophthalmol
July 2024
Department of Ophthalmology and Visual Sciences, Federal University of São Paulo (UNIFESP), São Paulo, São Paulo, Brazil.
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