Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?

Chem Sci

Laboratory of Macromolecular and Organic Chemistry , Eindhoven University of Technology, P.O. Box 513 , NL 5600 MB Eindhoven , The Netherlands . Email:

Published: March 2016

A library of water-soluble dynamic single-chain polymeric nanoparticles (SCPN) was prepared using a controlled radical polymerisation technique followed by the introduction of functional groups, including probes at targeted positions. The combined tools of electron paramagnetic resonance (EPR) and Overhauser dynamic nuclear polarization (ODNP) reveal that these SCPNs have structural and surface hydration properties resembling that of enzymes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968450PMC
http://dx.doi.org/10.1039/c5sc02319jDOI Listing

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