Osteoporosis is an insidious and increasingly prevalent disease that can cause fractures and affect patients' quality of life. The current study comparatively evaluates patients with and without loss of bone mass in terms of salivary calcium, viscosity, and pH. A controlled cross-sectional study was conducted in two groups of 32 postmenopausal women subjected to a bone densitometry scan and later referred for dental management at the Federal University of Minas Gerais, Brazil. The patients were assigned to two groups: Group 1 - patients with low bone mineral density (BMD) and Group 2 - patients without bone mineral changes. The following salivary parameters were evaluated: calcium concentration, flow rate, viscosity, pH, and average total protein. An oral examination was performed for assessment of DMFT variables and tongue coating. Data were analyzed using descriptive and inferential statistics, adopting a p-value < 0.05. The patients' mean age was 60 years (± 7.35). Salivary flow, pH, and viscosity were similar among the groups. Average total protein was 14.8 mg/mL and 19.0 mg/mL in Groups 1 and 2, respectively. Tongue coating and salivary calcium levels were significantly higher in Group 1 (p < 0.001). Salivary calcium is an important screening tool and may eventually be used for the diagnosis of bone mineral changes.
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http://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0054 | DOI Listing |
J Zhejiang Univ Sci B
December 2024
Department of Oral Pathology, Peking University School and Hospital of Stomatology / National Center of Stomatology / National Clinical Research Center for Oral Diseases / National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China.
In light of the lack of reliable molecular markers for odontogenic myxoma (OM), the detection of copy number variation (CNV) may present a more objective method for assessing ambiguous cases. In this study, we employed multiregional microdissection sequencing to integrate morphological features with genomic profiling. This allowed us to reveal the CNV profiles of OM and compare them with dental papilla (DP), dental follicle (DF), and odontogenic fibroma (OF) tissues.
View Article and Find Full Text PDFCureus
November 2024
Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Chennai, IND.
Introduction White spot lesions (WSLs) are opacities formed due to decalcification occurring in the enamel's subsurface layer. These lesions are most commonly seen in patients during and after fixed orthodontic treatment due to undisturbed accumulation of plaque. Other factors that can predispose to WSLs are enamel hypomineralization, hypomaturation, hypoplasia, and disruption in the levels of salivary calcium, phosphate, bicarbonate, and fluoride.
View Article and Find Full Text PDFStomatologiia (Mosk)
December 2024
Northern State Medical University, Arkhangelsk, Russia.
Objective: To study the associations between salivary minerals concentrations and caries experience among adolescents in the conditions of one of the industrial centers of the Far North.
Material And Methods: In total, 146 adolescents aged 15-17 years took part in a cross-sectional study in Syktyvkar, Komi Republic. Caries experience was assessed as DMFT index and its components.
J Oral Maxillofac Pathol
October 2024
Department of Oral Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Trace elements are the important components that play a crucial role in various functions of the human body at cellular and molecular levels. Considering the role of the trace elements in precancerous and cancerous conditions, estimation of their levels in these conditions could aid in understanding the disease process and progression. The purpose of this study is to determine the alteration in salivary electrolyte concentration of oral potentially malignant disorders (OPMD) and oral squamous cell carcinoma (OSCC) patients to correlate the variations with the severity and biological behaviour.
View Article and Find Full Text PDFArch Oral Biol
December 2024
R&D Headquarters, LION Corporation, 7-2-1 Hirai, Edogawa-ku, Tokyo 1320035, Japan.
Objective: This study aimed to compare the effects of a combination of sodium fluoride, soluble calcium, and pyrophosphate (FCaP) versus fluoride alone in inhibiting enamel caries progression.
Design: Different FCaP solutions were prepared, and two were selected for testing (FCaP-1: F = 76 mmol/L, Ca = 7.6 mmol/L, P = 7.
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