Land use function (LUF) is a valuable concept that allows for more integrated assessments of land system change. Identifying the changes and relationships of multiple LUFs is pertinent to land use planning and management. Selection and quantification of LUF indicators are critical for LUFs assessment. However, past studies have mostly assessed LUFs using socioeconomic data, which are not suitable for spatial variable quantification. In this study, we proposed a new LUFs classification system based on spatial planning goals, and we applied the system to assess 12 LUFs across 63 counties in Jiangsu Province of eastern China based on multi-source data using geospatial modeling tools combined with statistical analysis of socioeconomic data. We also analyzed the change in LUFs between 2000 and 2015, as well as the interactions among multiple functions. Finally, we identified distinct function zones based on the LUFs assessment in 2000 and 2015 using k-means clustering. The result showed that 12 LUFs displayed significant changes and interactions between 2000 and 2015, which can be explained by differing topography and social-ecological characteristics among counties. Additionally, we found four distinct LUF zones that are spatially agglomerated in similar landscapes and characterize specific LUF relationships in each cluster. In the future, local LUFs and their changes over time should be taken into consideration for land use planning and management, which provide a reference for policy-makers to make decisions that better match local development realities.
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http://dx.doi.org/10.1016/j.scitotenv.2018.05.383 | DOI Listing |
Clin Kidney J
January 2025
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Background: Arteriovenous fistulas (AVFs) in kidney transplant recipients are sometimes closed, either as a policy or due to complications. We collected data on the incidence of complications after AVF closure in a national cohort of transplanted patients.
Methods: Patients who received a kidney transplant between 2000 and 2015 and had a functional AVF that was later ligated or extirpated were included.
Cell Mol Biol Lett
January 2025
Enzymology and Metabolism Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367, Belvaux, Luxembourg.
Background: Metabolism is error prone. For instance, the reduced forms of the central metabolic cofactors nicotinamide adenine dinucleotide (NADH) and nicotinamide adenine dinucleotide phosphate (NADPH), can be converted into redox-inactive products, NADHX and NADPHX, through enzymatically catalyzed or spontaneous hydration. The metabolite repair enzymes NAXD and NAXE convert these damaged compounds back to the functional NAD(P)H cofactors.
View Article and Find Full Text PDFBackground: Cardiovascular‐kidney‐metabolic (CKM) health, a term recently defined by the American Heart Association, encompasses the interplay among metabolic, chronic kidney, and cardiovascular risk factors. We aimed to investigate the predictive significance of CKM disorders with the risk of cognitive decline and Alzheimer’s disease (AD) and AD‐related dementia (ADRD) mortality in a multiethnic population.
Method: We analyzed a cohort of 6,440 adults aged 45‐84 who participated in the Multiethnic Study of Atherosclerosis, with a baseline survey conducted in 2000‐2002, and were followed through to December 2015.
Alzheimers Dement
December 2024
Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA, USA
Background: Previous studies have linked sleep disturbances with an increased risk of dementia among older adults. However, the association between sleep patterns and brain health earlier in life is less understood. We aimed to determine how sleep in early midlife relates to an MRI‐derived indicator of brain age in late midlife.
View Article and Find Full Text PDFCancer Med
January 2025
Translational Medicine Research Unit, Medical Research Center Oulu, Oulu University Hospital, and University of Oulu, Oulu, Finland.
Background: Immune checkpoint inhibition therapies have provided remarkable results in numerous metastatic cancers, including mismatch repair-deficient (dMMR) colorectal cancer (CRC). To evaluate the potential for PD-1 blockade therapy in a large population-based cohort, we analyzed the tumor microenvironment and reviewed the clinical data and actualized treatment of all dMMR CRCs in Central Finland province between 2000 and 2015.
Material And Methods: Of 1343 CRC patients, 171 dMMR tumors were identified through immunohistochemical screening.
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