The results of overlapping metallic stents have been concerning but this practice is often unavoidable in the setting of long or tortuous lesions, diameter discrepancy of proximal and distal vessel, and for residual dissections. Theoretically, bio-absorbable scaffolds may carry an advantage over metallic stents due to the progressive resorption of the scaffold theoretically rendering the overlap a non-issue; this has not been clinically evident. Since stent/scaffold overlap cannot be entirely avoided, improved stent delivery/deployment and scaffold design modification may reduce complications in this complex patient subset.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/ccd.27662 | DOI Listing |
Front Vet Sci
June 2022
Dentistry and Oral Surgery Department, Small Animal Clinic, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.
Although periodontal disease is one of the most common (oral) diseases in dogs, an effective treatment approach to periodontitis lacks. The aim of this study was to evaluate the safety and efficacy of a regenerative, bio-absorbable implant biomaterial made of medical-grade porcine gelatin, which is cross-linked by transglutaminase into a porous scaffold for the treatment of periodontitis in dogs in a clinical setting. Nine client-owned dogs were included in this multicenter, prospective interventional clinical study.
View Article and Find Full Text PDFMater Today Bio
March 2022
College of Textiles & Clothing, Qingdao University, Qingdao, China.
Bio-textiles have aroused attractive attentions in tissue engineering and regenerative medicine, and developing robust, bio-absorbable, and extracellular matrix (ECM) fibril-mimicking nanofibrous textiles is urgently required for the renewal of existing microfibrous textile-based scaffolds and grafts. In this study, an integrated electrospinning system consisting of one nanoyarn-forming unit and one hot stretching unit is reported to fabricate silk fibroin (SF)/poly (L-lactic-acid) (PLLA) nanofibrous yarns (nanoyarns). The hot stretching process is demonstrated to significantly improve the fiber alignment, crystallinity, and mechanical properties of SF/PLLA nanoyarns, compared to the unstretched controls.
View Article and Find Full Text PDFPharmaceutics
September 2020
Faculty of Sustainable Design Engineering, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE C1A 4P3, Canada.
Herein, novel drug-eluting, bio-absorbable scaffold intended to cover piercing studs is introduced. This "biopierce" will stay in human tissue following piercing, and will slowly release an antimicrobial agent to prevent infection while the wound heals. Nearly 20% of all piercings lead to local infection.
View Article and Find Full Text PDFJ Funct Biomater
March 2020
Laboratory for Strength of Materials and Structures, Department of Civil Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
The high demand for biodegradable implants in bone fracture fixations has dramatically increased the use of polymers for biomedical applications as well. However, the replacement of stainless steel and titanium screws by biodegradable materials represents one of the most critical aspects of biomechanics. In this study, the mechanical behavior of polycaprolactone (PCL) in tension and compression is examined.
View Article and Find Full Text PDFJ Clin Periodontol
June 2019
Department of Oral and Maxillofacial Surgery, George-Augusta-University, Gottingen, Germany.
Background And Aims: To review the regenerative technologies used in bone regeneration: bone grafts, barrier membranes, bioactive factors and cell therapies.
Material And Methods: Four background review publications served to elaborate this consensus report.
Results And Conclusions: Biomaterials used as bone grafts must meet specific requirements: biocompatibility, porosity, osteoconductivity, osteoinductivity, surface properties, biodegradability, mechanical properties, angiogenicity, handling and manufacturing processes.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!