Overlapping bio-absorbable scaffolds: Aim for D2D technique?

Catheter Cardiovasc Interv

Mount Sinai School of Medicine, Cardiovascular Institute, One Gustave L. Levy Place, New York, New York.

Published: June 2018

The results of overlapping metallic stents have been concerning but this practice is often unavoidable in the setting of long or tortuous lesions, diameter discrepancy of proximal and distal vessel, and for residual dissections. Theoretically, bio-absorbable scaffolds may carry an advantage over metallic stents due to the progressive resorption of the scaffold theoretically rendering the overlap a non-issue; this has not been clinically evident. Since stent/scaffold overlap cannot be entirely avoided, improved stent delivery/deployment and scaffold design modification may reduce complications in this complex patient subset.

Download full-text PDF

Source
http://dx.doi.org/10.1002/ccd.27662DOI Listing

Publication Analysis

Top Keywords

bio-absorbable scaffolds
8
metallic stents
8
overlapping bio-absorbable
4
scaffolds aim
4
aim d2d
4
d2d technique?
4
technique? overlapping
4
overlapping metallic
4
stents concerning
4
concerning practice
4

Similar Publications

Treatment of Naturally Occurring Periodontitis in Dogs With a New Bio-Absorbable Regenerative Matrix.

Front Vet Sci

June 2022

Dentistry and Oral Surgery Department, Small Animal Clinic, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.

Although periodontal disease is one of the most common (oral) diseases in dogs, an effective treatment approach to periodontitis lacks. The aim of this study was to evaluate the safety and efficacy of a regenerative, bio-absorbable implant biomaterial made of medical-grade porcine gelatin, which is cross-linked by transglutaminase into a porous scaffold for the treatment of periodontitis in dogs in a clinical setting. Nine client-owned dogs were included in this multicenter, prospective interventional clinical study.

View Article and Find Full Text PDF

Bio-textiles have aroused attractive attentions in tissue engineering and regenerative medicine, and developing robust, bio-absorbable, and extracellular matrix (ECM) fibril-mimicking nanofibrous textiles is urgently required for the renewal of existing microfibrous textile-based scaffolds and grafts. In this study, an integrated electrospinning system consisting of one nanoyarn-forming unit and one hot stretching unit is reported to fabricate silk fibroin (SF)/poly (L-lactic-acid) (PLLA) nanofibrous yarns (nanoyarns). The hot stretching process is demonstrated to significantly improve the fiber alignment, crystallinity, and mechanical properties of SF/PLLA nanoyarns, compared to the unstretched controls.

View Article and Find Full Text PDF

Development of 3D Printed Drug-Eluting Scaffolds for Preventing Piercing Infection.

Pharmaceutics

September 2020

Faculty of Sustainable Design Engineering, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE C1A 4P3, Canada.

Herein, novel drug-eluting, bio-absorbable scaffold intended to cover piercing studs is introduced. This "biopierce" will stay in human tissue following piercing, and will slowly release an antimicrobial agent to prevent infection while the wound heals. Nearly 20% of all piercings lead to local infection.

View Article and Find Full Text PDF

Numerical Simulation of the Posterior Malleolus Fracture with the Finite Element Method.

J Funct Biomater

March 2020

Laboratory for Strength of Materials and Structures, Department of Civil Engineering, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

The high demand for biodegradable implants in bone fracture fixations has dramatically increased the use of polymers for biomedical applications as well. However, the replacement of stainless steel and titanium screws by biodegradable materials represents one of the most critical aspects of biomechanics. In this study, the mechanical behavior of polycaprolactone (PCL) in tension and compression is examined.

View Article and Find Full Text PDF

Background And Aims: To review the regenerative technologies used in bone regeneration: bone grafts, barrier membranes, bioactive factors and cell therapies.

Material And Methods: Four background review publications served to elaborate this consensus report.

Results And Conclusions: Biomaterials used as bone grafts must meet specific requirements: biocompatibility, porosity, osteoconductivity, osteoinductivity, surface properties, biodegradability, mechanical properties, angiogenicity, handling and manufacturing processes.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!