The use of medical cannabis in chronic illness is increasingly investigated, yet little is known about its use in paediatric populations. As child protection clinicians are often asked to provide advice around whether parents' actions to give medical cannabis to their chronically ill child constitutes harm or risk of harm, a review of the evidence base is required. This systematic review explores the use of cannabis-derived products in children with seizure disorders. While a reduction in seizure activity was observed in some children, included studies were poorly designed and too small to extrapolate reliable conclusions about clinical use. Due to the lack of high-quality evidence, the use of cannabis-derived products is currently not recommended in children with seizure disorders. However, in assessing risk and harm to subject children by child protection physicians in Australia with existing State and Territory legislation, evaluation must occur on a case-to-case basis with each instance considered on its individual merits. Clinical trials addressing drug efficacy and long-term safety of cannabis-derived products are required.
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http://dx.doi.org/10.1111/jpc.12876 | DOI Listing |
Brain Spine
July 2023
Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Tamil Nadu, India.
Emerging research highlights the potential neurobehavioral impacts of synthetic food dyes on children, prompting a reevaluation of their safety and regulatory standards. This letter discusses recent findings that associate synthetic food dyes with adverse behavioral outcomes, such as hyperactivity, particularly in children with or without identified behavioral disorders. It calls for updated regulatory guidelines that reflect current research, advocating for protecting children's behavioral health.
View Article and Find Full Text PDFJ Child Fam Stud
November 2022
University of Washington, PO Box 353600, Seattle, WA 98195-3600, USA.
Adolescents targeted for peer aggression are at risk of emotion dysregulation and social withdrawal-responses that predict increased victimization and impede the protective factors of peer support. This study examined victimized youth's emotions and social appraisals following four common third-party peer actions. African American, European American, Mexican American, and Native American adolescents ( = 257, 53% female, = 15 years) described their emotions and appraisals of third-party peer actions after the participants had been targets of peer aggression.
View Article and Find Full Text PDFJ Child Adolesc Psychiatr Nurs
February 2025
Department of Public Health Nursing, Faculty of Nursing, Gazi University, Ankara, Turkey.
Problem: Early adolescence (10-14 years) is a critical period in which peer victimization (PV) is common. In protecting, maintaining, and improving the health of adolescents, it is important to detect PV and evaluate its relationship with the level of hope and self-concept. This study aimed to determine the PV situation of adolescents living in rural areas and establish the effect of the level of hope and self-concept on this situation.
View Article and Find Full Text PDFInt J Mol Med
March 2025
Department of Clinical Laboratory, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Chongqing 400014, P.R. China.
Sepsis is often a cause of mortality in patients admitted to the intensive care unit. Notably, the heart is the organ most susceptible to the impact of sepsis and this condition is referred to as sepsis‑induced cardiomyopathy (SIC). Low triiodothyronine (T3) syndrome frequently occurs in patients with sepsis, and the heart is one of the most important target organs for the action of T3.
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