Evaluation of antihypertensive adherence and its determinants at primary healthcare facilities in rural South Africa.

J Comp Eff Res

Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Ga-Rankuwa, Pretoria 0208, South Africa.

Published: July 2018

AI Article Synopsis

  • The study aimed to analyze how well hypertensive patients in rural South Africa stick to their prescribed antihypertensive treatments and identify factors influencing their adherence.
  • Results showed that just 54.6% of patients adhered to their treatment, with good blood pressure control and having other health conditions positively impacting adherence, while smoking was a negative factor.
  • The findings indicated that while adherence and blood pressure control were generally low, adherence notably increased the likelihood of having controlled blood pressure; efforts are being made to enhance patient adherence in this area.

Article Abstract

Aim: To evaluate adherence to antihypertensive treatment in rural South Africa and identify potential determinants given concerns with adherence and its impact in this priority disease area. Patients & methods: Face-to-face interviews with hypertensive patients and rating their adherence to treatment using defined categorized responses. Associations between adherence and patient characteristics assessed and sensitivity analyses performed.

Results: 54.6% of patients were adherent to treatment. Controlled blood pressure (BP; odds ratios [OR] = 2.1; 95% CI: 1.1, 3.8; p = 0.019), comorbidity (OR = 2.0; 95% CI: 1.1, 3.6; p = 0.032) and smoking (OR = 0.3; 95% CI: 0.1, 0.8; p = 0.018) were associated with adherence.

Conclusion: Adherence and BP control were suboptimal, only smoking was an independent risk factor for adherence. Adherent patients were twice as likely to have controlled BP, although results were sensitive to the definition of adherence. Initiatives are in place to improve adherence, which will be monitored.

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Source
http://dx.doi.org/10.2217/cer-2018-0004DOI Listing

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