Phytochemical investigation of roots afforded five sesquiterpenes (), including two new sesquiterpenes 6-hydroxy-cyperenoic acid () and crassifterpenoid A (), together with three known compounds (). The structures of the new compounds were determined by comprehensive spectroscopic methods, and their absolute configurations were determined by quantum chemical ECD calculation. Crassifterpenoid A () is the first germacrane-type sesquiterpene isolated from , which enriched the diversity of chemical constituents in . In addition, the cytotoxicities of all compounds against human liver cancer lines HepG2 and Hep3B were determined, but none showed significant activity.
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| http://dx.doi.org/10.1080/10286020.2018.1465413 | DOI Listing |
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