The differential diagnosis for a focal brain lesion in a patient with systemic lupus erythematosus (SLE) is broad and includes infection, malignancy, and vascular and inflammatory etiologies. One rarely considered vascular pathology is cerebral venous thrombosis (CVT), which is often associated with a delay in diagnosis because of variable presentation and rare incidence. We present the case of a young woman with a new discrete brain lesion that appeared in the context of highly active SLE and was ultimately diagnosed with a CVT. We provide a literature review for diagnosis and management of cerebral venous thrombosis, a potentially serious complication of untreated systemic lupus erythematosus.
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| http://dx.doi.org/10.1155/2018/5862912 | DOI Listing |
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- A total of twelve patients were reviewed, predominantly middle-aged women, with common symptoms including headache and typical pSS manifestations such as dry mouth and arthritis.
- All patients received treatment including anticoagulants and recovered fully, highlighting the need for increased awareness and screening for autoimmune diseases in CVT cases, especially with unilateral transverse sinus involvement.
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