Mortality from Listeria monocytogenes meningoencephalitis following escalation to alemtuzumab therapy for relapsing-remitting Multiple Sclerosis.

Mult Scler Relat Disord

Bristol Brain Centre, Department of Neurosciences, North Bristol NHS Trust, Southmead Road, Westbury-On-Trym, BS10 5NB Bristol, United Kingdom. Electronic address:

Published: August 2018

We report the case of a patient who died from the rare complication of Listeriosis in the immediate phase following alemtuzumab administration one month after discontinuing dimethyl fumarate (DMF). There is considerable overlap with typical post-infusion symptoms therefore high surveillance and low threshold for empirical or possible prophylactic antibiotic therapy is advocated.

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http://dx.doi.org/10.1016/j.msard.2018.05.014DOI Listing

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