AI Article Synopsis
- The study evaluated the phytochemical content of Kei-apple fruit from Egypt, identifying chlorogenic acid and pyrogallol as the main phenolic compounds and malic acid as the most abundant organic acid.
- The whole fruit extract (WFE) demonstrated stronger antioxidant activity compared to the flesh extract (FE) and was determined to be safe at doses over 6000 mg/kg body weight.
- In toxicity tests, while male and female rats consuming 1000 mg/kg of WFE showed no significant changes in blood parameters, some biochemical alterations were noted, particularly in female rats.
Article Abstract
Present study was conducted to determine phytochemical constituents of Kei-apple fruit grown in Egypt, to evaluate antioxidant activity of the fruit extracts, and assess the safety of whole fruit extract (WFE) in acute and sub-chronic toxicity experiments using rats model. Chlorogenic acid and pyrogallol were the main identified phenolic compounds in dry fruits. Malic acid was the most abundant organic acid. The whole fruit extract exhibited higher antioxidant activity than the flesh extract (FE). The fatal dose of the extract is more than 6000 mg/kg b.w. In sub-chronic experiment, hemoglobin, red blood cells, total white blood cells and mean cell hemoglobin values did not significantly alter when male and female rats ingested 1000 mg/kg D. caffra WFE. Biochemical analysis showed some significant changes especially in female rats.
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| http://dx.doi.org/10.1016/j.foodchem.2018.05.099 | DOI Listing |
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