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http://dx.doi.org/10.1513/AnnalsATS.201804-259RLDOI Listing

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Article Synopsis
  • The study investigates the reliability of self-reported acute respiratory exacerbation episodes (AECOPD) among individuals with chronic obstructive pulmonary disease (COPD), suggesting that self-reports may not accurately reflect actual health records.
  • The researchers compared self-reported incidents of AECOPD with electronic health records from 511 participants, focusing on current or former heavy smokers, including those with and without COPD.
  • Findings revealed discrepancies, with a notable percentage of individuals documented in health records as having severe AECOPD not reporting such incidents themselves, highlighting the need for improved methods of identifying exacerbation tendencies in COPD patients.
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Background: Second-hand smoke (SHS) exposure appears to be more common among individuals with depression. However, self-report of SHS exposure is an inaccurate classification compared to confirming SHS exposure using urinary cotinine (UC). Additionally, the dose-response relationship between depression and UC is controversial.

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Oral squamous cell carcinoma (OSCC) biomarker studies rarely employ multi-omic biomarker strategies and pertinent clinicopathologic characteristics to predict mortality. In this study we determine for the first time a combined epigenetic, gene expression, and histology signature that differentiates between patients with different tobacco use history (heavy tobacco use with ≥10 pack years vs. no tobacco use).

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Introduction: The 2017 agreement between the U.S. Food and Drug Administration and the makers of Natural America Spirit (NAS) cigarettes restricted the use of "additive-free" (AF) in brand marketing, which the company replaced with "tobacco ingredients: tobacco & water" (TW), a phrase subsequently adopted by L&M.

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Environmental and occupational risk factors for COPD and its prevalence among miners worldwide: a Mendelian randomization and meta-analysis study.

Environ Sci Pollut Res Int

September 2023

Department of Occupational Health and Environment Health, School of Public Health, Anhui Medical University, Hefei, 230032, China.

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death after cardiovascular disease and stroke, and its incidence is associated with genetic, environmental, and occupational factors. Miner is high-risk population for COPD, but the global prevalence of COPD in this group is inaccurate. In this study, the environmental and occupational risk factors for COPD were explored comprehensively with a two-sample Mendelian randomization study by combining genome-wide association data from two large global sample sizes of publicly available databases, UK Biobank (n = 503,317) and FinnGen (n = 193,638), as well as the prevalence of COPD among miners was investigated with meta-analysis followed a random-effects model including seven studies (16,033 miners in total).

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