AI Article Synopsis

  • The study reviewed fetal MRI cases of meconium ileus (MI) and obstruction, focusing on distinguishing complicated MI through imaging features.
  • Seven cases were analyzed, revealing key MRI characteristics like the gradient appearance of bowel contents and an abnormal meconium signal, which were confirmed through surgical procedures.
  • The authors advocate for including fetal MRI in the diagnosis of suspected bowel obstruction during pregnancy to enhance risk assessment and management.

Article Abstract

Objective: To review fetal MRI cases surgically proven to have meconium ileus (MI) and obstruction, describe the common fetal MRI findings that distinguish cases of complicated MI, and to compare these findings with surgical images and perinatal outcomes.

Method: We performed a retrospective review of all fetal MRI examinations and the corresponding medical record from our tertiary care children's hospital over an 18-month period. Postnatal management and outcomes were reviewed for these patients, and those patients with surgical or postmortem diagnosis of complicated MI were included in the study.

Results: Our analysis revealed 7 cases. In this cohort, 3 imaging features of the fetal bowel were repeatedly seen: gradient appearance of intraluminal bowel contents, abnormally localized meconium signal, and collapsed appearance of the colon on MRI. Surgical diagnoses confirmed MI. All live-born infants underwent surgical repair.

Conclusion: Fetal MRI should be included in the diagnostic algorithm of any pregnancy where fetal bowel obstruction is suspected to better risk stratify patients.

Download full-text PDF

Source
http://dx.doi.org/10.1002/pd.5296DOI Listing

Publication Analysis

Top Keywords

fetal mri
20
meconium ileus
8
review fetal
8
fetal bowel
8
fetal
7
surgical
5
mri
5
mri management
4
management complicated
4
complicated meconium
4

Similar Publications

Purpose: We sought to evaluate the incidence, natural history, and management of cystic spinal lesions following myelomeningocele/myeloschisis closure.

Methods: We performed a single-center retrospective review of all patients who underwent myelomeningocele/myeloschisis closure from 2013 to 2018 with follow-up to 5 years old.

Results: We analyzed 100 fetal repairs and 81 postnatal closures from 305 total surgeries.

View Article and Find Full Text PDF

Two novel variants in associated with anophthalmia and congenital cystic eye.

Ophthalmic Genet

January 2025

Department of Ophthalmology, Unidade de Saúde Local de São João, Porto, Portugal.

Purpose: We present the case of a newborn with right anophthalmia, left congenital cystic eye, and two novel variants in the gene. This report provides a comprehensive discussion of the clinical presentation, management strategies, and long-term follow-up for this rare condition.

Methods: A thorough ophthalmic examination was performed.

View Article and Find Full Text PDF

Objective: The objective of this study was to identify a novel gene and its potential mechanisms associated with susceptibility to gestational diabetes mellitus (GDM) through an integrative approach.

Methods: We analyzed data from genome-wide association studies (GWAS) of GDM in the FinnGen R11 dataset (16,802 GDM cases and 237,816 controls) and Genotype Tissue Expression v8 expression quantitative trait locus data. We used summary-data-based Mendelian randomization to determine associations between transcript levels and phenotypes, transcriptome-wide association studies to provide insights into gene-trait associations, multi-marker analysis of genomic annotation to perform gene-based analysis, genome-wide complex trait analysis-multivariate set-based association test-combo to determine gene prioritization, and polygenic priority scores to prioritize the causal genes to screen candidate genes.

View Article and Find Full Text PDF

Therapeutic hypothermia in preterm infants under 36 weeks: Case series on outcomes and brain MRI findings.

Eur J Pediatr

January 2025

Neonatology Department. Hospital Sant Joan de Déu, Center for Maternal Fetal and Neonatal Medicine. Neonatal Brain Group, Universitat de Barcelona. Hospital Clínic, Universitat de Barcelona. BCNatal - Barcelona, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.

Purpose: Perinatal hypoxic-ischemic encephalopathy (HIE) is a significant cause of neonatal brain injury. Therapeutic hypothermia (TH) is the standard treatment for term neonates, but its safety and efficacy in neonates < 36 weeks gestational age (GA) remains unclear. This case series aimed to evaluate the outcomes of preterm infants with HIE treated with TH.

View Article and Find Full Text PDF
Article Synopsis
  • Emphysematous pyelonephritis (EPN) is a severe urinary tract infection that can lead to high mortality rates, particularly in cases with underlying conditions, but it's rarely reported.
  • A 32-year-old pregnant woman with type 2 diabetes experienced worsening symptoms of pyelonephritis, leading to a diagnosis of EPN through imaging techniques.
  • Successful treatment involved antibiotic therapy, emphasizing the importance of early diagnosis and customized treatment approaches to safeguard both maternal and fetal health during pregnancy.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!