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Phototoxic reaction to oral terbinafine due to Tinea capitis in a child.
Acta Dermatovenerol Croat
November 2024
Prof. Ana Bakija-Konsuo, MD, PhD, Clinic for Dermatovenerology CUTIS, Vukovarska 22, Dubrovnik, Croatia;
We report the case of an 18-month-old boy who developed a phototoxic skin reaction to terbinafine on his scalp, ears, and face in the form of disseminated erythematous plaques, which resembled subacute lupus erythematosus (SCLE) in their clinical presentation. Skin changes appeared a short time after the boy was exposed to sunlight during the period of time when he was treated with oral terbinafine due to Microsporum canis fungal scalp infection. Tinea capitis is a common dermatophyte infection primarily affecting prepubertal children (1).
View Article and Find Full Text PDFExploring the Impact of IL-33 Gene Polymorphism () on Susceptibility to Chronic Spontaneous Urticaria and Its Association with Serum Interleukin-33 Levels.
Int J Mol Sci
December 2024
Department of Anatomy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 400006 Cluj-Napoca, Romania.
Urticaria is a debilitating skin condition affecting up to 20% of the global population, characterized by erythematous, maculopapular lesions and significant quality of life impairment. This study focused on the role of interleukin 33 (IL-33) and its polymorphisms, particularly SNP , in chronic spontaneous urticaria (CSU). Using demographic, clinical, and laboratory data from CSU patients and controls, we estimated allele and genotype frequencies, Hardy-Weinberg equilibrium condition, and serum IL-33 levels, using unconditional binomial logistic regression for association analysis.
View Article and Find Full Text PDFRash Evaluation in a Transplant Patient.
Ann Clin Lab Sci
September 2024
Department of Pediatrics, Division of Infectious Diseases, State University of New York Health Sciences University, Brooklyn, NY, USA.
Article Synopsis
- A 62-year-old male lung transplant recipient developed a sudden rash two months after starting new medications, raising concerns about a potential drug allergy.
- Skin biopsy results indicated a drug reaction, but the patient's treatment with high-dose prednisone complicated allergy testing.
- The case highlights the challenges in diagnosing drug allergies in transplant patients, emphasizing the need for better diagnostic strategies to avoid misdiagnosis and improve care.
Association of BLK and BANK1 gene polymorphisms with systemic lupus erythematous in Egyptian patients.
Egypt J Immunol
October 2024
Department of Medical Microbiology and Immunology, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
This study examined the genotype, allelic frequencies (polymorphisms) in a sample of Egyptian patients and examined the relationship between disease activity in systemic lupus erythematosus (SLE) and the B lymphoid tyrosine kinase (BLK) and B-cell scaffold protein with ankyrin repeats 1 (BANK1) gene. This case control study involved 70 SLE patients and 40 subjects matched for age and sex as a control group. Clinical data were gathered from each participant, including SLE-related clinical activity indicators.
View Article and Find Full Text PDFA clinical case of pityriasis lichenoides chronica presenting with palpable purpura after streptococcal infection.
Folia Med (Plovdiv)
June 2024
Sofiamed University Hospital, St Kliment Ohridski University, Sofia, Bulgaria.
Article Synopsis
- Pityriasis lichenoides is a rare inflammatory skin condition characterized by red-brown papules and crusty lesions as they evolve over time.
- A 60-year-old woman developed the chronic form of this condition ten days after suffering from streptococcal pharyngitis, starting with purple spots on her legs and later developing red, scaly patches on other parts of her body.
- After treatment with methylprednisolone and hydroxychloroquine, her skin lesions improved significantly and did not return.
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