Correction: MiR-124 acts as a target for Alzheimer's disease by regulating BACE1.

Oncotarget

Medicinal Chemistry and Pharmacology Institute, Inner Mongolia University for The Nationalities, Tongliao, Inner Mongolia, P.R. China.

Published: May 2018

[This corrects the article DOI: 10.18632/oncotarget.23119.].

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973865PMC
http://dx.doi.org/10.18632/oncotarget.25461DOI Listing

Publication Analysis

Top Keywords

correction mir-124
4
mir-124 acts
4
acts target
4
target alzheimer's
4
alzheimer's disease
4
disease regulating
4
regulating bace1
4
bace1 [this
4
[this corrects
4
corrects article
4

Similar Publications

Patients with autism spectrum disorder (ASD) typically experience substantial social isolation, which may cause secondary adverse effects on their brain development. miR-124 is the most abundant miRNA in the human brain, acting as a pivotal molecule regulating neuronal fate determination. Alterations of miR-124 maturation or expression are observed in various neurodevelopmental, neuropsychiatric, and neurodegenerative disorders.

View Article and Find Full Text PDF

Promoter Hypomethylation of miR-124 Gene Is Associated With Major Depressive Disorder.

Front Mol Neurosci

December 2021

Department of Psychiatry, Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Based on our previous studies and other evidence, miR-124 is an important biomarker and therapeutic target for major depressive disorder (MDD). The aim of this study was to clarify the role of miR-124 methylation in MDD and antidepressant effects from the perspective of epigenetics. MethylTargetâ„¢ was used to detect methylation levels of the three miR-124 precursor genes (MIR124-1, MIR124-2, and MIR124-3) in 33 pre- and post-treatment MDD patients and 33 healthy controls.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!