AI Article Synopsis
- The study evaluated the effectiveness of three CE-marked rapid diagnostic tests (RDTs) for detecting anti-HCV antibodies in plasma samples.
- Out of 200 plasma samples, the RDTs showed sensitivity ranging from 71% to 99% and specificity from 78% to 100%.
- Multisure achieved the highest sensitivity at 99%, while First Response had a notable specificity of 90%, prompting recommendations for further research to create a testing algorithm in Cameroon.
Article Abstract
Objective: This study was aimed at evaluating the performance of three CE-marked rapid diagnostic tests (RDTs): Multisure-HCV, First Response and Toyo; for screening anti- HCV antibody using plasma samples.
Results: Overall, 200 plasma samples were used. Sensibility and specificity of these RDTs range from 71 to 99 and 78 to 100% respectively. Multisure scored a sensitivity at 99% (95% CI 97-100%) and First Response reached a specificity at 90% (95% CI 85-94.9%). Further studies should be conducted to establish an algorithm using these RTDs for the detection of HCV infection in Cameroon.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989429 | PMC |
| http://dx.doi.org/10.1186/s13104-018-3465-8 | DOI Listing |
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