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bioRxiv
December 2024
Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Neurons require high amounts energy, and mitochondria help to fulfill this requirement. Dysfunctional mitochondria trigger problems in various neuronal tasks. Using the neuromuscular junction (NMJ) as a model synapse, we previously reported that Mitochondrial Complex I (MCI) subunits were required for maintaining NMJ function and growth.
View Article and Find Full Text PDFAnimals (Basel)
November 2024
School of Biosciences and Veterinary Medicine, University of Camerino, Via Pontoni 5, 62032 Camerino, Italy.
(1) Background: Respiratory problems may be associated with pathogens among which viruses may play an important role in causing or promoting clinical signs. However, traditional diagnostic methods for equine infectious diseases, such as PCR, are limited to known pathogens and often miss rare or novel viruses. Metagenomic next-generation sequencing is a transformative method that allows the sequencing of all genomes present in a sample.
View Article and Find Full Text PDFJ Pathol Transl Med
November 2024
Department of Pathology, CHA University School of Medicine, CHA Gangnam Medical Center, Seoul, Korea.
Cervical cancer screening during pregnancy presents unique challenges for cytologic interpretation. This review focuses on pregnancy-associated cytomorphological changes and their impact on diagnosis of cervical intraepithelial neoplasia (CIN) and cervical cancer. Pregnancy-induced alterations include navicular cells, hyperplastic endocervical cells, immature metaplastic cells, and occasional decidual cells or trophoblasts.
View Article and Find Full Text PDFUnlabelled: In otorhinolaryngology, the question of improving the tactics of early postoperative management in patients who have undergone surgery on the structures of the nasal cavity remains open. The timing of rehabilitation, the possible outcome of postoperative inflammation of the mucous membrane and the patient's ability to work depend on the choice of tactics. The nasal cavity differs from other anatomical areas in its rich blood supply, and therefore the problem of adequate hemostasis in the early stages after undergoing surgical treatment is still extremely relevant.
View Article and Find Full Text PDFDiagn Cytopathol
February 2025
Medicine and Surgery, Al-Rayan Colleges, Madinah, Saudi Arabia.
Background: It is widely known that tobacco use significantly contributes to a variety of health problems, including mouth cancer. The proteins P16 and Ki-67 have a role in regulating the cell cycle and promoting cell growth. Analyzing the levels of these proteins can give us valuable information about the overall health of cells.
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