Background: In the United States' changing health care climate, an updated picture of evidence-based practice (EBP) in the hospital setting is needed. Researchers explored EBP activities that interdisciplinary therapy team members used most frequently to acquire and appraise clinical evidence, therapists' perceptions of EBP, and barriers and enablers to EBP implementation within two similar acute-care hospitals in the Midwest.
Methods: An electronic survey was distributed to 190 therapy practitioners working in two acute-care hospital settings. Eighty-four practitioners completed the 54-item electronic survey (n=84; 44% response rate). The sample consisted of 21 speech-language pathologists, 19 occupational therapists, 30 physical therapists, and 14 physical or occupational therapy assistants.
Results: Practitioners reported utilizing past experience and colleague interaction most frequently to acquire and appraise evidence; participants used self-reflective activities, such as journal clubs and carrying out research, infrequently. All disciplines placed high personal and professional value on EBP but indicated only moderate amounts of workplace support and personal preparedness to acquire, critique, and implement evidence. All disciplines indicated time was the largest EBP barrier. For enablers of EBP, disciplines responded differently, reporting support in the form of resources, training, and departmental goals.
Conclusion: Pooled results indicated EBP activities used most frequently were of the lowest levels of clinical evidence; more effective EBP activities, such as self-reflection and participation in research, were rarely used. Hospital-based interdisciplinary therapy practitioners valued EBP but reported workplace constraints limiting implementation. Barriers to EBP were similar across disciplines, while enablers differed between disciplines.
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Handb Exp Pharmacol
January 2025
Certara, Canterbury, UK.
The application of quantitative systems pharmacology (QSP) has enabled substantial progress and impact in many areas of therapeutic discovery and development. This new technology is increasingly accepted by industry, academia, and solution providers, and is enjoying greater interest from regulators. In this chapter, we summarize key aspects regarding how effective collaboration among institutions and disciplines can support the growth of QSP and expand its application domain.
View Article and Find Full Text PDFOrthopadie (Heidelb)
January 2025
Westdeutsches Diabetes- und Gesundheitszentrum, Verbund Katholischer Kliniken Düsseldorf, Hohensandweg 37, 40591, Düsseldorf, Deutschland.
Background: The prevalence of obesity has increased significantly in recent years and is a causal risk factor for the development of type 2 diabetes. Moreover, chronic degenerative joint diseases are also triggered by obesity.
Weight Loss: Both obesity-related secondary diseases-type 2 diabetes and chronic degenerative joint disease-can be prevented or at least delayed by lifestyle intervention aimed at weight reduction.
Schmerz
January 2025
University Pain Center, University Hospital Carl Gustav Carus, Dresden, Germany.
In addition to the usual evaluation approach (usually a clinical randomized trial in the sense of the question: does an intervention work), complex interventions require further systematic investigations to prove their effectiveness. The role of the context in which the intervention is delivered is essential here, as is consideration of the question of why an intervention works (or does not work). Detailed recommendations exist for the planning and implementation of effectiveness studies on complex interventions, to which interdisciplinary multimodal pain therapy undoubtedly belongs.
View Article and Find Full Text PDFSchmerz
January 2025
UniversitätsSchmerzCentrum, Klinik für Anästhesiologie, Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Deutschland.
In addition to the usual evaluation approach (usually a clinical randomized trial in the sense of the question: does an intervention work), complex interventions require further systematic investigations to prove their effectiveness. The role of the context in which the intervention is delivered is essential here, as is consideration of the question of why an intervention works (or does not work). Detailed recommendations exist for the planning and implementation of effectiveness studies on complex interventions, to which interdisciplinary multimodal pain therapy undoubtedly belongs.
View Article and Find Full Text PDFAliment Pharmacol Ther
January 2025
Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Brain-gut behaviour therapies (BGBT) have gained widespread acceptance as therapeutic modalities for the management of disorders of gut-brain interaction (DGBI). However, existing treatment evaluation methods in the medical field fail to capture the specific elements of scientific rigour unique to behavioural trial evaluation.
Aims: To offer the first consensus on the development and testing of BGBT in DGBI.
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