AI Article Synopsis
- Recent research shows that health is linked to the microbes in our bodies, and high-tech sequencing has revealed more info about these microbial changes in various diseases.
- Disbiome is a new database that organizes and presents information on microbiota linked to diseases, using a standard classification system and linking microbes to established taxonomies.
- This database is unique as it provides a thorough, up-to-date overview of how microbial compositions vary in diseases, supported by quality assessments of included studies, making it easier for users to navigate and find relevant data.
Article Abstract
Background: Recent research has provided fascinating indications and evidence that the host health is linked to its microbial inhabitants. Due to the development of high-throughput sequencing technologies, more and more data covering microbial composition changes in different disease types are emerging. However, this information is dispersed over a wide variety of medical and biomedical disciplines.
Description: Disbiome is a database which collects and presents published microbiota-disease information in a standardized way. The diseases are classified using the MedDRA classification system and the micro-organisms are linked to their NCBI and SILVA taxonomy. Finally, each study included in the Disbiome database is assessed for its reporting quality using a standardized questionnaire.
Conclusions: Disbiome is the first database giving a clear, concise and up-to-date overview of microbial composition differences in diseases, together with the relevant information of the studies published. The strength of this database lies within the combination of the presence of references to other databases, which enables both specific and diverse search strategies within the Disbiome database, and the human annotation which ensures a simple and structured presentation of the available data.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987391 | PMC |
| http://dx.doi.org/10.1186/s12866-018-1197-5 | DOI Listing |
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