AI Article Synopsis
- * Seventeen healthy male volunteers participated in the trial, where they fasted overnight before taking mastiha, and blood samples were collected to analyze amino acid levels.
- * We identified 24 out of 60 amino acids, with notable decreases in branched-chain valine, proline, and ornithine at specific time intervals post-ingestion, indicating that terpenes can affect amino acid levels in the body.
Article Abstract
We aimed to explore whether plasma-free amino acids are modified in response to terpenes administration in healthy humans. In this open-label, single-arm acute trial, seventeen healthy male volunteers were administered with a naturally occurring product of known terpenes-namely mastiha-after overnight fasting. Blood samples were collected at different time points before and after ingestion. We aimed at identifying and quantifying 60 free amino acids in plasma applying Gas Chromatography-Mass Spectrometry. A total of 24 free amino acids were quantified. Branched-chain valine significantly decreased 4 h post-ingestion, whereas proline decreased at 6 h and ornithine at 2 h, compared to 0 h. These novel findings demonstrate that free amino acids levels are modulated in response to terpenes intake in healthy subjects.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024789 | PMC |
| http://dx.doi.org/10.3390/nu10060715 | DOI Listing |
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