AI Article Synopsis

Article Abstract

In foreign literature on research into the etiopathogenesis of autism spectrum disorders (ASDs), the division of this group of diseases into two forms is getting more and more frequent. These two forms are 'syndromal' and 'non-syndromal' forms of autistic disorders. The literature review aims to cover the issues of the dichotomous classification of ASDs based on the genetic and molecular psychiatric views on the etiopathogenesis of this group of diseases. It also covers the purpose of this classification, the opportunities of its usage in routine clinical practice and the network resources, which allow classifying a form of ASD correctly. Special attention is paid to the multidisciplinary approach to dichotomous classification and its difference from the clinical view on the systematization of autism and the importance of this method for selection of target therapy.

Download full-text PDF

Source
http://dx.doi.org/10.17116/jnevro201811841107-112DOI Listing

Publication Analysis

Top Keywords

autism spectrum
8
spectrum disorders
8
group diseases
8
dichotomous classification
8
[dichotomous classification
4
classification autism
4
disorders syndromal
4
syndromal non-syndromal
4
non-syndromal forms]
4
forms] foreign
4

Similar Publications

Objective: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by social communication differences and restricted interests. One proposed biologic mechanism underlying ASD is oxidative stress, leading to the clinical use of glutathione based on anecdotal reports of improved behavior in autistic children. In this pilot study, we tested this observation using a randomized clinical trial format to collect preliminary data on glutathione safety and efficacy.

View Article and Find Full Text PDF

Deficits in sensorimotor gating have been reported in individuals with autism spectrum disorder (ASD), as well as in ASD murine models. However, this behavior has not been examined in the neuronal subset-specific (NS)- knockout (KO) model of ASD. KO mice exhibit hyperactivity of the PI3K/AKT/mTOR signaling pathway which is implicated in the onset of autistic deficits.

View Article and Find Full Text PDF

Promoting playfulness through a play-based occupational therapy intervention: A study protocol.

Afr J Disabil

December 2024

Department of Occupational Therapy, Faculty of Medicine and Health Science, Stellenbosch University, Cape Town, South Africa.

Background: Play is integral to optimal childhood development. Occupational therapists often use play to improve play skills. However, when it comes to learners with autism spectrum disorder (ASD) in South Africa, there is limited research regarding play-based interventions that address the underlying motivators of play, namely, social play and playfulness.

View Article and Find Full Text PDF

Bibliometric analysis of trends in dental management of the children with Autism Spectrum Disorder (ASD).

Discov Ment Health

January 2025

Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

This study aimed to present a complete overview of the trends, difficulties, and improvements in dental treatment for children diagnosed with autism spectrum disorder through rigorous bibliometric analysis. The dimensional database field was chosen to enable the inclusion and recall of the greatest number of relevant entries. All peer-reviewed international journals published between 2004 and 2023 were included in this study.

View Article and Find Full Text PDF

Many children with ASD exhibit difficulties with emotion regulation that greatly impair functioning. Certain intrinsic correlates of dysregulation have been identified in this population, but the search for potential environmental influences has been less fruitful. The current study examined several aspects of parenting as correlates of observed regulation in Autistic children, as measured in both parent-child and independent regulatory contexts.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!