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[Comorbidity of epilepsy and chronic disorders in children and adolescents with the assessment of the effectiveness of therapy]. | LitMetric

Aim: To determine the comorbidity of epilepsy and chronic tic disorders (HTR) in children and adolescents based on the results of video-EEG monitoring and treatment efficacy.

Material And Methods: One hundred and sixteen patients diagnosed with HTR, 83 boys and 33 girls, aged from 3 to 15 years, were studied. Clinical psychoneurological examination, psychological testing and video-EEG monitoring were performed at the first stage of the study. An effect of treatment was assessed at the second stage.

Results And Conclusion: The high prevalence of epileptiform activity was observed in 46.6% of patients with HTR, comorbidity of epilepsy and chronic tic disorders in 16.4%. Antiepileptic drugs, in particular extended release valproate (depakine chronosphere), are most effective for both epilepsy and tic disorders.

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http://dx.doi.org/10.17116/jnevro20181184136-42DOI Listing

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