Symmetrical peripheral gangrene (SPG) is rare but devastating complication which is characterized by symmetrical ischemic change of the distal extremities. In this report, we describe our management protocol for SPG, focusing on surgical approaches. Between January 2007 and February 2016, 10 thoracodorsal artery perforator (TDAP) free flaps were performed in 6 patients with SPG. Three patients were male and mean age was 56 (range, 44-69) years. All the patients were in shock. The causes of shock were sepsis in 4 cases, respiratory arrest in 1 case, and hypovolemia in 1 case. Eight transmetatarsal amputations and 2 Lisfranc amputations were performed. Flap sizes ranged from 7 × 11 cm to 25 × 15 cm. There were 3 cases of partial necrosis of the flap: two healed conservatively with dressings and one required skin graft. Three of the patients were later able to walk independently at Functional Ambulation Classification (FAC) level 6, one patient could walk independently on level surfaces at FAC level 5, and 2 could walk independently using walking aids, classified at FAC level 4. The average follow-up period was 18 (range, 6-54) months. In patients with SPG, minimal bone amputation and foot salvage with TDAP flaps were successful. Separate reconstruction of bone and soft tissue had good outcomes.
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http://dx.doi.org/10.1155/2018/6508607 | DOI Listing |
Chaos
January 2025
Departamento de Física, Universidad Nacional de Colombia, Bogotá, Colombia.
We consider a discrete-time Markovian random walk with resets on a connected undirected network. The resets, in which the walker is relocated to randomly chosen nodes, are governed by an independent discrete-time renewal process. Some nodes of the network are target nodes, and we focus on the statistics of first hitting of these nodes.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Orthopedics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok, Thailand.
Among control methods for robotic exoskeletons, biologically inspired control based on central pattern generators (CPGs) offer a promising approach to generate natural and robust walking patterns. Compared to other approaches, like model-based and machine learning-based control, the biologically inspired control provides robustness to perturbations, requires less computational power, and does not need system models or large learning datasets. While it has shown effectiveness, a comprehensive evaluation of its user experience is lacking.
View Article and Find Full Text PDFBackground: Mild traumatic brain injury (mTBI) increases dementia risk. Delays in diagnosis are common due to insensitive tools, prolonging symptoms and time to treatment. Dual-task gait and functional mobility deficits are present post-mTBI and in people living with dementia (PWD); however, it is unclear whether dual-tasking can be used as a tool to differentiate between groups.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Huashan Hospital, Fudan University, Shanghai, Shanghai, China.
Background: Frailty, a condition characterized by functional decline, is recognized as a potential modifiable risk factor for dementia prevention. Genetic risk is also considered an unregulated risk for dementia. However, their joint effect remains unclear.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Faculdade Ciências Médicas de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Background: Gait speed is an important measure in the evaluation of elderly patients. The gait speed reduction is associated with high-impact outcomes such as: loss of functionality, frailty and increased mortality. Several clinical conditions lead to a reduction in gait speed.
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