One known bis-indole alkaloid-voacamine was isolated from Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding promoting activity to PTP1B.
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One bis-indole alkaloid-voacamine from Stapf: biological activity evaluation of PTP1B utilizing enzymology method based on SPRi expriment.
Nat Prod Res
December 2019
School of Basic Medical Sciences, The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, Institute of Innovation, Chengdu University of Traditional Chinese Medicine, Chengdu , P R China.
One known bis-indole alkaloid-voacamine was isolated from Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding promoting activity to PTP1B.
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