Rationale: Despite the approval of antiangiogenic therapy for high grade glioma (HGG) patients, survival benefits are still limited. New treatment plans have always been developed to improve the survival.
Patient Concerns: A 26-year-old woman was admitted to our hospital for distending pain of head and eye.
Diagnoses: Resonance imaging (MRI) revealed a large spherical heterogeneously enhancing, mixed cystic and solid mass in the right frontal region, and the midline shifted.
Intervention: The patient received apatinib therapy for positive vascular endothelial growth factor.
Outcomes: A partial response was observed after 4 weeks and remains sustained until now.
Lessons: It suggests that apatinib might be a feasible option for the treatment in advanced HGG patients or patients with poor physical condition.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392728 | PMC |
| http://dx.doi.org/10.1097/MD.0000000000010859 | DOI Listing |
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