AI Article Synopsis
- Ovarian cancer peritoneal carcinomatosis requires a comprehensive treatment strategy, addressing recurrent malignant ascites and its underlying mechanisms.
- The role of peritoneal washing cytology for identifying metastases and the significance of pre-treatment Ca-125 levels are key to understanding disease progression and treatment options.
- The update highlights the importance of cytoreductive surgery, hyperthermic intraperitoneal chemotherapy, and ongoing clinical trials in optimizing outcomes for patients with this aggressive form of cancer.
Article Abstract
Ovarian cancer peritoneal carcinomatosis requires a multimodal-treatment approach. Current treatment considerations are analyzed in this update and include the management of recurrent malignant ascites and the understanding of its pathophysiology, the role of peritoneal washing cytology in detecting peritoneal metastases, capsular invasion and ovarian cancer histologic type, interpretation of pretreatment Ca-125 levels at different time points of ovarian cancer therapeutic management, characteristics of 10-year survivors of high-grade ovarian cancer, and the role of lymphadenectomy in ovarian cancer peritoneal carcinomatosis. This update also includes current considerations on the role of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in ovarian cancer peritoneal carcinomatosis as well as relevant ongoing phase III randomized controlled trial protocols.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907426 | PMC |
| http://dx.doi.org/10.1155/2018/5284814 | DOI Listing |
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