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An integrative analysis reveals cancer risk associated with artificial sweeteners.
J Transl Med
January 2025
Medical College of YiChun University, Xuefu Road No 576, Yichun, 336000, Jiangxi, People's Republic of China.
Background: Artificial sweeteners (AS) have been widely utilized in the food, beverage, and pharmaceutical industries for decades. While numerous publications have suggested a potential link between AS and diseases, particularly cancer, controversy still surrounds this issue. This study aims to investigate the association between AS consumption and cancer risk.
View Article and Find Full Text PDFImpact of cold plasma-assisted Non-thermal deamidation and glycosylation on the construction of sugar derivative-zein conjugates for enhancing pickering foam stability: Technical principles and molecular interactions.
Food Res Int
January 2025
State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Science and Engineering, Tianjin University of Science & Technology, No. 9, No. 13 Ave., TEDA, Tianjin 300457, China. Electronic address:
There is an urgent need for stable, plant-based Pickering foams to address the growing consumer demand for sustainable, low-calorie, aerated sweet foods. This study employed a cold plasma-assisted deamidation and glycosylation (CPDG) approach to promote hydrophilic reassembly of zein, resulting in the formation of sugar derivative-zein conjugates. This was accomplished by coupling deamidated zein with polyhydroxy sugars including sucralose (Suc), maltitol (Mal), mannitol (Man), and stevioside (Ste).
View Article and Find Full Text PDFSucralose-Enhanced Adipogenesis on Preadipocyte Human Cell Line During Differentiation Process.
Int J Mol Sci
December 2024
Laboratorio Universitario de Análisis Clínicos e Investigación, Universidad de Sonora (LUACI) Departamento de Ciencias Químico-Biológicas y Agropecuarias, Campus Navojoa. Lázaro Cárdenas del Río #100, CP 85880 Navojoa, Sonora, Mexico.
Sucralose, a commonly nonnutritive sweetener used in daily products of habitual diet, is related to impairing the gut microbiome by disrupting inflammatory response, promoting weight gain by increasing adipose tissue and promoting chronic inflammatory processes. Considering the impact of sucralose in the development of metabolic diseases, in this work, we focused on the impact of sucralose on the adipocyte differentiation process to determine if sucralose can promote adipogenesis and increase adipose tissue depots in PCS 210 010 human preadipocytes cell line. Sucralose at 25 (S25) and 100 ng/µL (S100) concentrations were tested against control with no edulcorant (NS) during the adipocyte differentiation process at 48 h and 96 h.
View Article and Find Full Text PDFMass load and source apportionment of pharmaceutical and personal care product in the Wuhan section of the Yangtze River, China.
Sci Total Environ
December 2024
Hubei Key Laboratory of Mineral Resources Processing and Environment, School of Resources and Environmental Engineering, Wuhan University of Technology, Wuhan 430070, China; The James Hutton Institute, Craigiebuckler, Aberdeen AB15 8QH, UK. Electronic address:
Given the limited research on pharmaceuticals and personal care products (PPCPs) in the Wuhan section of the Yangtze River (WYR), this work investigated the distribution of 15 PPCPs in this region, assessed their ecological risks and annual fluxes. It was further to analyze the levels of indicator sucralose in the WYR to understand the sources of PPCPs. The results showed the average concentrations were 143.
View Article and Find Full Text PDFArtificial Sweeteners in US-Marketed Oral Nicotine Pouch Products: Correlation with Nicotine Contents and Effects on Product Preference.
Nicotine Tob Res
December 2024
Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA.
Introduction: Artificial sweeteners, sucralose and acesulfame-k, are listed as ingredients of oral nicotine pouches (ONPs), a product category with rapidly growing market share. The exact quantities of these sweeteners in ONPs remain unknown. Artificial sweeteners in ONPs may reduce aversion, facilitate initiation and encourage consumption behavior.
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