A Practical and Chemoselective Ammonia-Free Birch Reduction.

Org Lett

College of Science , China Agricultural University, No. 2 Yuanmingyuan West Road , Beijing 100193 , China.

Published: June 2018

A novel protocol for a significantly improved, practical, and chemoselective ammonia-free Birch reduction mediated by bench-stable sodium dispersions and recoverable 15-crown-5 ether is reported. A broad range of aromatic and heteroaromatic compounds is reduced with excellent yields.

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Source
http://dx.doi.org/10.1021/acs.orglett.8b00891DOI Listing

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