Isolation of Phenolic Derivatives and Essential Oil Analysis of (L.) Lindl. Aerial Parts.

Iran J Pharm Res

Department of Pharmacognosy, Faculty of Pharmacy and Medicinal Plant Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Published: January 2017

(L.) Lindl. (Apiaceae) is a medicinal plant distributed in Mediterranean regions, Caucasia and southwest of Asia. In the present study phytochemical constituents of the extract obtained from the aerial parts of were investigated using various chromatographic and spectroscopic methods. Essential oil of the plant aerial parts was also analyzed using GC-MS. Five phenolic derivatives, isoimperatorin (1), ferudenol (2), caffeic acid glucosyl ester (3), isorhamnetin-3-O-β-D-glucopyranoside (4) and quercetin-3-O-β-D-glucopyranoside (5) were isolated from the aerial parts of and their structures were elucidated using H-NMR, C-NMR, EI-MS and UV spectral analyses. Twenty-seven compounds were also identified in the essential oil of plant aerial parts, of which β-pinene (43.1%), α-pinene (22.1%) and -δ3-carene (16.9%) were characterized as main compounds. The results of this study introduce as a source of potentially bioactive phenolic compounds and suggest it as an appropriate candidate for further studies.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963662PMC

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